Depression Clinical Trial
Official title:
Clinical Outcomes With Electroconvulsive Therapy: Insights From Computational Modelling
This study will generate new information on how to optimise brain targets with ECT stimulation.
This study will differentiate the brain regions which are related to the effectiveness of electroconvulsive therapy (ECT) as a treatment, from the brain regions associated with memory impairment, with ECT stimulation. This will be done by 1) testing effects on memory of 4 different forms of ECT, which stimulate the brain differently; 2) in a subset of participants, use computer modelling to assess the pattern of brain stimulation with the 4 forms of ECT, and match these results to memory outcomes. ;
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