Olfactory and Visual Perception in Depressed Patients

Depression Clinical Trial

— PERODEP  

Official title:

Study of the Emotional Reactivity to Olfactive and Visual Perception in Depressed Patients

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT02857088
• Other study ID #: P/2011/126
• Status: Terminated
• Phase: N/A
• First received: July 26, 2016
• Last updated: August 2, 2016
• Start date: February 2014
• Est. completion date: April 2016

Study information

• Verified date: August 2016
• Source: Centre Hospitalier Universitaire de Besancon
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Agence Nationale de Sécurité du Médicament et des produits de santéFrance: Committee for the Protection of Personnes
• Study type: Interventional

Clinical Trial Summary

The study aimed to determine the emotional reactivity of depressed patients to visual and olfactory stimuli in comparison with healthy volunteers.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 3
• Est. completion date: April 2016
• Est. primary completion date: April 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• no cognitive impairment that could prevent instruction comprehension

• no more than 10 cigarettes/day

• signed informed consent

• group 1: current major depressive disorder

• group 2: no current major depressive disorder

Exclusion Criteria:

• pregnancy

• visual impairment

• olfactory impairment

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Depression

Intervention

Behavioral:
• olfactory assessment
determination of olfactory sensitivity through olfactory threshold assessment (butanol) determination of hedonicity and intensity of 16 usual odors
• image visualization
20 images (from the IAPS-international affective picture systems) are presented to the subject. He has to determine the hedonicity of each picture.
• psychophysiological assessment
during the olfaction assessment and the image visualization, skin conductance reactivity (SCR) is recorded to assess unconscious emotional reactivity

Locations

Country	Name	City	State
France	CHU Besancon	Besancon	Doubs

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de Besancon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	hedonicity score of visual stimuli	it will be compared between depressed and non depressed subjects.	up to 1 month	No
Primary	skin conductance reactivity amplitude	it will be compared between depressed and non depressed subjects.	up to 1 month	No
Primary	Skin conductance reactivity reaction time	it will be compared between depressed and non depressed subjects.	up to 1 month	No
Primary	hedonicity score of olfactory stimuli	it will be compared between depressed and non depressed subjects.	up to 1 month	No