First Experimental Study of Transference Work - In Teenagers (FEST-IT)

Depression Clinical Trial

— FEST-IT  

Official title:

First Experimental Study of Transference Work - In Teenagers

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01531101
• Other study ID #: Sykehuset i Vestfold
• Secondary ID: REK: 2011/1424 F
• Status: Completed
• Phase: N/A
• Start date: January 2012
• Est. completion date: March 2019

Study information

• Verified date: March 2020
• Source: Sykehuset i Vestfold HF
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The First Experimental Study on Transference work - In Teenagers (FEST-IT) will be a randomized clinical trial, which will be designed to explore effects of transference work in dynamic psychotherapy in adolescents with major depressive disorder (MDD). The design of the study is a so-called dismantling design, in which a single component is added and/or varied to an existent treatment method (psychodynamic psychotherapy). Thus, the efficiency of a specific technique (transference interventions) can be identified.

The primary hypothesis is that the transference group may have a more favorable course over time than will the comparison group.

The second hypothesis is that patients with a history of low Quality of Object Relations score and/or personality disorders—might benefit more from therapy with transference work than from therapy without.

The third hypothesis is that female adolescents may have better treatment effect of transference work than male adolescents.

Description:

The effect of transference interventions in depressed adolescents and the moderator moderating effect of quality of object relations, personality disorder and gender will be explored. Methods and study design: The First Experimental Study of Transference Work-In Teenagers (FEST-IT) will be a randomized clinical trial with a dismantling design. The study is aimed to explore the effects of transference work in psychodynamic psychotherapy for adolescents with depression. One hundred patients ages 16 to 18 years old will be randomized to one of two treatment groups, in both of which general psychodynamic techniques will be used. The quality of adolescents' relationships will be a central focus of the study.The patients will be treated over 28 weeks with either a moderate level of transference intervention or no transference intervention. Follow-up will be at 1 year after treatment termination.

Gender personality disorder (PD) and quality of object relations (QOR) will be the preselected moderators.

The object of this clinical trial is to explore the effect of transference interventions in psychodynamic psychotherapy in adolescents with a major depressive disorder. Using a randomized and dismantling design, we hope that the study will add more specific knowledge to the evidence base.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 70
• Est. completion date: March 2019
• Est. primary completion date: March 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 16 Years to 18 Years

Eligibility

Inclusion Criteria:

• Adolescents aged 16 - 18 years

Exclusion Criteria:

• Pervasive developmental disorder,

• psychosis, or substance abuse

Related Conditions & MeSH terms

• Depression

Intervention

Behavioral:
• Individual psychodynamic psychotherapy
Individual psychodynamic psychotherapy with or without transference work. I.e. with or without relational therapist interventions focusing on the patient-therapist relationship.

Locations

Country	Name	City	State
Norway	BUP vest, Diakonhjemmet sykehus	Oslo
Norway	Nic Walls Institutt, Lovisenberg Diakonale Sykehus	Oslo
Norway	Oslo University Hospital	Oslo
Norway	Spcialist in psychiatry and clinical psychiatry	Oslo
Norway	University of Oslo	Oslo
Norway	Research Unit, Division of	Tønsberg	Vestfold

Sponsors (2)

Lead Sponsor	Collaborator
Randi Ulberg	University of Oslo

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Adolescent Relationship Scale (ARS)	Patient rated Visual-Analogues scales	Current
Primary	Psychodynamic Functioning Scales (PFS)	Average of 5 subscales rated by experienced clinician raters; family relations, friendships, tolerance for affects, insight, problem solving and adaptive capacity	3 months
Primary	Inventory of Interpersonal Problems-Circumplex Version (IIP-C)	64.items patient rated measure	Currentl
Secondary	Global Assessment of Functioning (GAF)	Rated by experienced clinician raters	One week
Secondary	Symptom Checklist-90 (Global Severity Index; GSI)	Patient-rated	Current
Secondary	Beck Depression Inventory (BDI)	Patient rated	Current
Secondary	Montgomery Åsberg Rating Scale (MADRS)	Rated by therapist and/or experienced clinician rater	Current

External Links

•   Sykehuset i Vesthold
•   The Central Norway Regional Ethics Health Committee
•   Ulberg R, Hersoug AG, Høglend P.(2012)Treatment of adolescents with depression: the effect of transference interventions in a randomized controlled study of dynamic psychotherapy.Trials. 2012 Sep 6;13:159. doi: 10.1186/1745-6215-13-159.
•   University of Oslo