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Clinical Trial Summary

The purpose of this study is to determine whether electroconvulsive therapy (ECT) has an influence on pressure within the human brain before, during and after ECT.


Clinical Trial Description

1. Aim:

1. Our main objective concerning this study is to determine to what extent ECT does lead to an increase of the Pulsatility Index (as an indicator of intracerebral pressure) measured by a Transcranial Doppler Device (TCD).

2. As a secondary objective we want to compare the PI measurements with simultaneously measured systemic blood pressure.

2. Study design:

a.Observational study: cohort study

3. Treatment:

a. Treatment as usual, PI and blood pressure measurement at baseline, just before ECT, during and 5 minutes after ECT. Data will be collected during unilateral treatment during 3 consecutive ECT treatments.

4. Endpoints:

1. A minimum of sixteen patients are needed according to the power analysis. ;


Study Design

Observational Model: Cohort, Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT00597831
Study type Observational
Source Rijnstate Hospital
Contact
Status Completed
Phase N/A
Start date January 2008
Completion date July 2009

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