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Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity

Dentin Sensitivity Clinical Trial

Official title:
Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity

Clinical Trial Summary

Evaluate the safety and clinical efficacy of new dental desensitizers in the treatment of dentin sensitivity, including the relief of sensitivity symptoms and the duration of efficacy.

Clinical Trial Description

This is a randomized, single-blind and controlled study to include 40 patients with dentin sensitivity. The study will be a randomized controlled trial with split mouth control, with two quadrants of the same patient as test and control groups, the test group being the group using the new desensitizer and the control group being the group with the clinically used desensitizer (Gruma desensitizer). Improvement in dentin sensitivity symptoms was the primary outcome indicator observed. Dentin sensitivity was assessed by evaluating the reduction in dentin sensitivity VAS scores at immediately, 1 month, 3 months, and 6 months points after the desensitization treatment, and by evaluating the subjects' self-reported relief of sensitivity. Safety was assessed by evaluating appliance defects and adverse events at the immediately,1-, 3-, and 6-months points after the desensitization treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06378255
Study type Interventional
Source Peking University Hospital of Stomatology
Contact Qianqian Wang
Phone +86-10-62173403
Email wangqian0213@163.com
Status Recruiting
Phase N/A
Start date March 20, 2024
Completion date September 1, 2025
View Details
See also
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Completed NCT02293044 - A Study to Evaluate the Safety and Efficacy of an Oxalate Strip on Adjacent Teeth With Dentinal Hypersensitivity N/A
Completed NCT02128633 - Effectiveness of a Homecare Dentin Hypersensitivity Gel Phase 2/Phase 3
Completed NCT03310268 - A Clinical Study to Evaluate a Stannous Fluoride Toothpaste for the Relief of Dentinal Hypersensitivity N/A
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