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Dentin Hypersensitivity clinical trials

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NCT ID: NCT04591444 Completed - Dentin Sensitivity Clinical Trials

Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity

Start date: January 2017
Phase: Phase 3
Study type: Interventional

Dentin hypersensitivity (DH) can be defined as acute, short-duration pain from open dentin tubules in exposed dentin. The symptom of DH is subjective and varies from patient to patient and may present as mild discomfort or as a high-intensity pain, which can affect the individual's quality of life, interfering with their eating and hygiene habits. One approach to treatment would be the use of agents that chemically desensitize sensory nerves, blocking the transmission of nerve stimuli to the central nervous system. The effectiveness of desensitizing treatments is influenced by several factors present in the oral cavity, which can contribute to a greater effect of these agents but can also be responsible for removing them from the dental surface. To date, studies have been carried out in the short term, not exceeding an average period of 12 weeks, so there is no consensus on the technique or agent that will guarantee the most effective and lasting effect against DH, not even the ideal period for reapplication. Thus, more studies are needed to assess the clinical behavior of desensitizing products on the market, especially the most recent releases. Therefore, the aim of this study was to clinically compare the effectiveness of different office treatments for DH, being ClinproTM White Varnish, ClinproTM XT Varnish, and a control group (placebo) through pain assessment with the Visual Analog Scale (VAS), after stimulation with air from the triple syringe.

NCT ID: NCT04527159 Completed - Clinical trials for Dentin Hypersensitivity

Comparison of Desensitizing Materials

Start date: January 6, 2019
Phase: N/A
Study type: Interventional

To compare the efficacy of two commercially available in-office desensitizing agents (Fluoraphat Pro and VivaSens®), in the treatment of dentinal hypersensitivity.

NCT ID: NCT04512625 Completed - Clinical trials for Dentin Hypersensitivity

Desensitizers in Reducing Post Tooth Preparation Sensitivity for a Fixed Dental Prosthesis

Start date: November 28, 2019
Phase: N/A
Study type: Interventional

The main purpose of the present study was to evaluate and compare the effectiveness of three kinds of commercially available desensitizing agents: Gluma, Sheildforce plus, and Telio CS desensitizers in reducing the pre- and post-cementation sensitivity for full coverage restorations.

NCT ID: NCT04422184 Completed - Clinical trials for Periodontal Diseases

Comparative Clinical Evaluation of Three Different Agents in Reducing Dental Hypersensitivity in Periodontal Patients

Start date: July 29, 2019
Phase: Phase 4
Study type: Interventional

The present project will compare the effect of DH reduction using three different dentifrices (Sensodyne Repair and Protect - NOVAMIN technology; Dentalclean Daily Regenerator - REFIX technology; Dentalclean Daily Regenerator - REFIX technology + potassium citrate) in periodontal patients. The evaluation will be in 6 moments: T1 and T2- immediately before and after scaling and root planing (SRP) procedures; T3-after polishing sensitive areas with rubbers cups and the dentifrice determined for each group of patients and T4, 5, 6- After 2, 4 and 8 weeks of SRP. Profissional assessments and patient perception data will be performed.

NCT ID: NCT04249336 Completed - Clinical trials for Dentin Hypersensitivity

Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH

Start date: September 27, 2019
Phase: Phase 3
Study type: Interventional

This will be multi-centered, triple blinded, randomized, four parallel treatments assigned study to compare clinical efficacy of commercially available dentifrices with placebo for immediate and sustained relief from Dentin Hypersensitivity after short term use. Condition or disease: Dentin hypersensitivity Intervention/Treatment: Product 1; Fluoro-Calcium-Phospho-silicate based BioMin F Product 2; Pro-Argin formula based Colgate Sensitive Pro-Relief Product 3; Strontium Acetate based Sensodyne Rapid Action Product 4; Sodium Fluoride based Colgate Total

NCT ID: NCT04225247 Completed - Clinical trials for Dentin Hypersensitivity

Efficacy of Seventh Generation Bonding Agents as Short-Term Desensitizers Among Patients With Hypersensitivity

Start date: March 7, 2018
Phase: Phase 3
Study type: Interventional

The world lacks a gold standard treatment for treating dentin hypersensitivity. Fluoride varnish is most commonly used as a treatment but it causes temporary discoloration of tooth structure and may cause irritation or burning of gums when it comes in contact with gums. Seventh generation bonding agents are less technique sensitive and are easy to use. The present study aims to find out the better seventh generation bonding agent as a treatment option for sensitivity. A total of 105 patients with dentin hypersensitivity are randomized into three groups. Scaling and root debridement are performed for all the groups. This study compares two seventh generation bonding agents and taking fluoride varnish as control group.

NCT ID: NCT03965039 Completed - Clinical trials for Dentin Hypersensitivity

A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity

Start date: July 8, 2019
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the efficacy (changes in dentinal hypersensitivity) and safety (oral soft tissue evaluation) after use of one of four dentifrices in subjects with pre-existing hypersensitivity over an 11-week period.

NCT ID: NCT03943095 Completed - Dentin Sensitivity Clinical Trials

Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity

Start date: May 13, 2019
Phase: Phase 2
Study type: Interventional

This exploratory study will characterize the efficacy profile of an experimental dual active 5 percent (%) potassium nitrate/0.454% stannous fluoride dentifrice, compared to a single active 0.454% stannous fluoride desensitizing dentifrice, over an 8-week treatment period.

NCT ID: NCT03851900 Completed - Clinical trials for Dentin Hypersensitivity

A Comparison of Long-Term Effectiveness of Two Desensitizing Products

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

This randomized, controlled, clinical trial aimed to compare the 6- month clinical performance of a desensitizer that contains calcium phosphate TM with a two-step self-etch adhesive SE and placebo (distilled water). At least 150 teeth wil be treated with desensitizing products and placebo randomly one third usig TM, one third using SE and one third using placebo. The efficiency of the materials will be evaluated at baseline, 1 week, 1 month, 3 months and 6 months after treatment.

NCT ID: NCT02936830 Completed - Clinical trials for Dentin Hypersensitivity

Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity

Start date: October 2016
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare the efficacy of dentine hypersensitivity reduction using in office paste formula containing nanoHydroxyapatite with the commercially available fluoride (duraphat) and a placebo in treating hypersensitivity in a single visit.