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Dental Pulp Necrosis clinical trials

View clinical trials related to Dental Pulp Necrosis.

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NCT ID: NCT04035330 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative Pain

Start date: September 2019
Phase: N/A
Study type: Interventional

To compare the effect of using Etidronate in sodium hypochlorite versus sodium hypochlorite irrigating solution on: - Postoperative pain in patients with necrotic pulp. - Bacterial load reduction & main bacterial species detected preinstrumentation and post-instrumentaion - Periapical Matrix metalloproteinase 9 level (MMP-9) postinstrumentation and pre-obturation

NCT ID: NCT04035083 Not yet recruiting - Pulp Necroses Clinical Trials

Laser Activated Irrigation Versus Passive Ultrasonic Irrigation

Start date: September 2019
Phase: N/A
Study type: Interventional

assessment of bacterial reduction and post-operative pain following Laser activated irrigation using sodium hypochlorite and a 980 nm diode laser device as an adjunct to conventional root canal treatment, and comparing it with passive ultrasonic irrigation using sodium hypochlorite and an ultrasonic device in patients with single rooted asymptomatic necrotic teeth.

NCT ID: NCT04035070 Not yet recruiting - Necrotic Pulp Clinical Trials

Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria

Start date: January 2021
Phase: Phase 4
Study type: Interventional

• The aim of this study is to compare the degree of postoperative pain and the antimicrobial effect in terms of bacterial count reduction after using co-amoxiclav-clindamycin solution versus MTAD and sodium hypochlorite irrigating solutions in patients with necrotic pulp.

NCT ID: NCT03813433 Not yet recruiting - Pulp Necrosis Clinical Trials

Discoloration of Endosequence and Mineral Trioxde Aggregate in Revascularization of Necrotic Immature Permanent Teeth

Start date: June 2023
Phase: N/A
Study type: Interventional

the objective of this study is to evaluate post operative pain after using Endosequence versus Mineral Trioxide Aggregate as coronal plug material in revascularization of non vital immature anterior teeth

NCT ID: NCT03717337 Not yet recruiting - Pulp Necrosis Clinical Trials

Success Rate of Single Versus Two Visit Regenerative Treatment Protocol in Non Vital Mature Anterior Teeth

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This study evaluates success rate of non vital mature anterior teeth with periapical lesion treated by regenerative endodontic protocol in single visit versus two visit technique. Patients are randomized into two groups where treatment will be done either in one visit including access, disinfection, placing platelet rich plasma as scaffold and restoration or two visit protocol involving access, disinfection and placing calcium hydroxide as intracanal medicament in first visit followed by a second visit after 3 weeks involving reopening of the tooth, removing intracanal medicament and placing platelet rich plasma as scaffold then restoration. Success rate is defined as absence of subjective signs and symptoms along with healing of periapical lesion

NCT ID: NCT03698188 Not yet recruiting - Necrotic Pulp Clinical Trials

Comparative Evaluation of the Regenerative Capacity of Two Platelet Concentrates

Start date: November 2018
Phase: N/A
Study type: Interventional

Injectable platelet-rich fibrin (I-PRF) is a flowable blood concentrate that is entirely natural and allows ease of access and flow within the root canal. It was first developed in 2014 by modifying the centrifugation parameters. I-PRF has great potential in the field of endodontics. At present, it is still in its infancy and needs to be explored with regard to its regenerative efficacy. To the best of our knowledge, this study is the first to clinically and comparatively investigate Platelet-rich plasma (PRP) and I-PRF.

NCT ID: NCT03690960 Not yet recruiting - Necrosis, Pulp Clinical Trials

Antimicrobial Effect of Modified Antibiotic Nanofibers for Regenerative Endodontics Procedures

Start date: December 2018
Phase: N/A
Study type: Interventional

The treatment for immature teeth with pulp necrosis can be carried out through apexification or regenerative endodontics procedures including platelet rich plasma (PRP), platelet rich fibrin (PRF) and injectable PRF, these techniques used alone or in combination. Revascularization therapy carries on more advantages than apexification, such as inducing root-end development and reinforcement. However, apical repair will not happen in the presence of inflamed and infected tissue.the aim of this study is to evaluate the antimicrobial effect of pre-synthesized novel antibiotic loaded electrospun nanofibers used in patients with immature necrotic teeth.

NCT ID: NCT03668899 Not yet recruiting - Clinical trials for Dental Pulp Necrosis

Antimicrobial Efficacy of Four Different Irrigation Protocols

Start date: August 2019
Phase: N/A
Study type: Interventional

proper disinfection of root canal system before obturation is a must for long term success of endodontic treatment, therefore a proper irrigant is mandatory, therefore investigators are studying the antibacterial effects of 4 different irrgating solutions in root canal treatment of patients diagnosed with necrotic pulps in their mandibular posterior teeth. patients will be recruited from outpatient clinic of the endodontic department in cairo university. endodontic treatment will be carried out as usual and samples from the infected root canals will be collected before and after preparation to be cultivated and analyzed at the laboratories of microbiology of faculty of medicine, cairo university

NCT ID: NCT03504332 Not yet recruiting - Pulp Necroses Clinical Trials

Revascularization of Immature Anterior Necrotic Teeth

Start date: June 2018
Phase: Phase 3
Study type: Interventional

The object of this study is to compare the effect of Calcium Hydroxide and Di-antibiotic paste as intracanal disinfectants in the 1st visit of revascularization of necrotic immature permanent anterior teeth.

NCT ID: NCT03301259 Not yet recruiting - Necrotic Pulp Clinical Trials

Postoperative Pain Following Treatment of Asymptomatic Necrotic Mandibular Molars in Single Visit Using Wave-one Reciprocating Instruments Versus One-Shape Rotary Instruments

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the post treatment pain after instrumentation of root canals with a single file reciprocating (Wave-One Ni Ti file, DENTSPLY Maillefer) or rotary(One Shape, Micro Mega, France) file system in patient with asymptomatic necrotic molars This trial will help to clinically evaluate the use of reciprocating motion in endodontic treatment in necrotic teeth without periapical lesion therefore reduce the post-obtuation pain