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Dental Pulp Diseases clinical trials

View clinical trials related to Dental Pulp Diseases.

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NCT ID: NCT04793477 Recruiting - Clinical trials for Pulp Disease, Dental

Effectiveness of Rotating System and Single File Reciprocating System in Temporal Molars

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

Is an in vivo study to test the effectiveness of the reciprocating system Reciproc blue and the rotating system VDW.ROTATE in primary molars.

NCT ID: NCT04636450 Recruiting - Dental Pulp Disease Clinical Trials

Manual and Rotatory Instrumentation Pulpectomy in Primary Mandibular Molars

RotaPulp
Start date: December 8, 2020
Phase: N/A
Study type: Interventional

In this study, the aim is to compare manual and rotatory pulpectomy techniques on 100 primary mandibular molars on children between the ages of 4 and 8 years. The plan is to conduct a randomized controlled trial with a 1:1 ratio for group allocation at a teaching university pediatric dentistry clinic between January 2021 and December 2021. Two manual systems, as well as two rotary systems, will be randomly assigned. The adult manual system used will be K-file and the adult rotary system will be K3. The pediatric manual system used in this study will be Kedo-SH, while the pediatric rotary system will be Kedo-S. The observed outcome measures in this study are the following: 1) instrumentation and filling time; 2) filling quality by radiographic evaluation; 3) postoperative pain levels using the visual analog scale at 12 and 24 hours; and 4) frequency of complications (e.g. fistulas, thinning of the mesiodistal walls, periapical or furcation radiolucency) after a 3-, 6-, 9-, and 12-month follow-up.

NCT ID: NCT04528979 Recruiting - Clinical trials for Endodontically Treated Teeth

Outcome of Endodontic Treatment and Retreatment With a Bioceramic Sealer

Start date: September 20, 2019
Phase: N/A
Study type: Interventional

This study is a prospective randomized controlled study of patients who come to the University. The aim is to evaluate the success rate of treatment and retreatment of canals using BioRoot ™ RCS cement compared with AH Plus up to 6 years of follow-up. The null hypothesis is that there will be no statistically significant differences in rates of successful treatment of root canals filled with BioRoot ™ RCS compared to gutta-percha and AH Plus sealer.

NCT ID: NCT04527705 Recruiting - Clinical trials for Endodontically Treated Teeth

Outcome of Endodontic Retreatment in One or Two Visits

Start date: September 20, 2018
Phase: N/A
Study type: Interventional

This study is a prospective randomized controlled study of patients who come to the University and non-surgical root canal retreatment is considered as the election of choice in presence of periapical disease. The aim is to evaluate the success rate of non-surgical retreatment performed in one compared to two visit treatment up to 10 years of follow-up. The null hypothesis is that there will be no statistically significant differences in rates of success, when performing root canal non-surgical retreatment in one or two visits.

NCT ID: NCT04471558 Recruiting - Endodontic Disease Clinical Trials

Effect of Music on Young Practitioner's Stress During Endodontic Treatment

MUSIQUENDO
Start date: November 9, 2020
Phase:
Study type: Observational

According to several studies, patients consider endodontic treatment as one of the most stress-inducing dental procedures. Two studies demonstrated that music enables the patient to be less stressed during RCT. RCTs are also stressful for the practitioner, and particularly for students who start their dental practice. Endodontic and prosthetic cares are considered the most demanding by students. RCT requires high degree of precision in gestures and patience because those technical acts are, in part, blindly realised and can be long. In a preliminary study, it was found that the most stress-inducing steps for the students during endodontic treatment are root-canal preparation and filling. The beneficial side of listening to music on the patient's stress during RCT has been proved; but to our knowledge, no study assessed the effect of listening to music on the stress of the practitioner and more particularly of the young practitioner, during endodontic treatment, and in particular during root canal preparation. This is the main aim of this study.

NCT ID: NCT04243993 Recruiting - Endodontic Disease Clinical Trials

Clinical Outcomes of Bio-MA and ProRoot MTA in Endodontic Treatment

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the endodontic outcomes of Bio-MA and ProRoot MTA in pulpotomy, orthograde MTA apical barrier, root perforation repair, endodontic microsurgery.

NCT ID: NCT03883295 Recruiting - Clinical trials for Pulp Disease, Dental

Evaluation of Clinical and Radiological Success of Vital Amputation Treatment

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Total amputation therapy; is a treatment method aimed at maintaining the vitality of the radicular pulp remaining as a result of complete removal of coronal pulp tissue. In cases where pulp is exposed due to caries or trauma, the pulp is vital, bleeding can be controlled during the procedure, no periapical pathology is seen and radicular pulp is healthy. Traditionally, acute pulp pain is thought to be a symptom of irreversible pulpitis, and it is thought that there is little chance of the pulp returning to its normal situation after removal of the irritants. Root canal treatment has been accepted as the gold standard for the treatment of these symptoms. In recent studies, spontaneous or severe pain before procedure has not always indicated that pulp has no repair capacity, and deep carious lesions are not necessarily associated with irreversible pulpal pathology. Histological studies showed that even when caries reach the pulp or degeneration and inflammation were seen in it, there was a healthy section still present in the pulp. Therefore, it is stated that the healthy pulp remaining as a result of total amputation performed by removal of degenerated pulp can be preserved. Furthermore, it is stated that for the healing potential of the remaining pulp tissue, the original signal should be that the bleeding can be controlled after the amputation of the infected pulp tissue. While the most popular method in the treatment of vital pulp is CaOH, the American Academy of Pediatric Dentistry has been reported to be more resistant to dissolution in the protocol in recent years. MTA is a more suitable material because it is more homogeneous, and forms a thicker dentin bridge. However, the MTA requires a long time to harden, it is difficult to manipulate and color. In recent years, researchers have focused on creating new MTA formulations to improve their physicochemical properties without affecting their biocompatibility and bioactivity. NeoMTA Plus is a new fine powder tricalcium silicate. It consists of a water-based gel and powder mixture and the powder-gel mixing ratio may vary depending on the area of use. It is a material similar to MTA Plus. However, in order to avoid tooth discoloration, tantalium oxide used instead of the bismuth oxide and required calcium hydroxide used to induce the formation of mineralized tissue.

NCT ID: NCT03451435 Recruiting - Endodontic Disease Clinical Trials

N-Acetyl Cysteine Protects Pulpal Stem Cells in Endodontic Revascularization

NAC
Start date: June 15, 2018
Phase: Early Phase 1
Study type: Interventional

Pulp re-vascularization/regeneration is a procedure performed to allow pulpal stem cells to survive and/or differentiate to allow immature tooth root structures to grow to full maturity. Currently, the procedure includes disinfection of the necrotic root canal space and induction of bleeding to potentiate pulpal stem cell differentiation to allow root growth on an immature root. A number of studies conducted previously demonstrate that N-acetyl cysteine (NAC) potentiates differentiation of pulpal stem/stromal cells and protects pulpal cells from apoptosis. 14-18 human subjects will be recruited forming two groups where pulp re-vascularization/regeneration procedures will be performed with or without the use of NAC treatment prior to induction of bleeding. Recall follow-up appointments will be done at 6 months and 1 year post treatment with subsequent yearly appointments until full root growth has been achieved.

NCT ID: NCT03410134 Recruiting - Clinical trials for Pulp Disease, Dental

Assessment of Vital Pulp Therapy in Permanent Molars

Start date: November 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the long term clinical performance of vital pulp therapy of young permanent teeth with irreversible pulpitis

NCT ID: NCT02286648 Recruiting - Pulpitis Clinical Trials

Success Rate Evaluation of Miniature Pulpotomy With MTA in Primary Molars

Start date: February 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the clinical and radiographic success rate of Miniature pulpotomy with Mineral Trioxide Aggregate (MTA) in primary molars.