Clinical Trials Logo

Clinical Trial Summary

HHT is a relative rare autosomal dominant inherited disorder of the fibrovascular tissue. Diagnosis of HHT is often delayed for decades (Pierucci 2012). However, it would be desirable to achieve an early diagnosis as early screening and treatment decrease disease-associated complications and increase life expectancy (Kroon 2018). Our approach is a nationwide call and awareness campaign to dentists in Germany, as nearly all persons visit a dentist from time to time. This approach is promising to us, as most patients develop nosebleeds and multiple, typical telangiectases of the skin or mucosa. A predilection site is the oral mucosa and the face, including the lips (Shovlin 2000).


Clinical Trial Description

The German self-help group is taking down the number of inquiries from patients and physicians per months since April 2017. In June 2018 an article about HHT is planned to be published in the journal of the German dental association and the Federal Association of Fund Dentists of Germany. This journal is distributed to all dentists in Germany and is a set book for them. Total circulation in 2017 was 77,621 (http://www.aerzteverlag.de/portfolio/fachwissen-medizindental/zm-zahnaerztliche-mitteilungen /profil/ ). The article describes the case of visceral abscesses after dental screening in a patient with HHT and pulmonary arteriovenous malformations. These could probably have been prevented if the dentist had prescribed an antibiotic prophylaxis to the patient. The article includes a call to search for telangiectases. If those are seen the dentist is recommended to ask the patient if he or relatives have nosebleeds. If both apply, the dentist is asked to inform the patient about HHT and give him the address of the national German self-help group. After 3 and 6 months a reminder shall be published in the same journal. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03549949
Study type Observational
Source University Hospital, Essen
Contact
Status Active, not recruiting
Phase
Start date June 1, 2018
Completion date July 2022

See also
  Status Clinical Trial Phase
Completed NCT04191200 - Oral Status of Patients Suffering From SCHIZophrenia Followed at Charles Perrens Hospital
Completed NCT02205619 - Amount of Cementum After Scaling, Root Planing and Glycine Air Polishing Phase 2/Phase 3
Active, not recruiting NCT05597956 - Effectiveness of Infiltration With Resin in Treatment of MIH Incisors in Children Showing Opacities N/A
Not yet recruiting NCT06081868 - RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda N/A
Recruiting NCT03851224 - Immediate Implant With no Graft , Autogenous Graft or Xenograft. N/A
Completed NCT04005456 - Personalized Lifestyle Intervention for Improving Functional Health Outcomes Using N-of-1 Tent-Umbrella-Bucket Design N/A
Completed NCT04153266 - Oral Epithelial Dysplasia Informational Needs Questionnaire
Enrolling by invitation NCT05157009 - Immediate Implant Outcomes With and Without Bone Augmentation N/A
Completed NCT03729167 - Instrumentation Effectiveness of Modified, Area-Specific Hand Scalers During Non-Surgical Periodontal Therapy N/A
Completed NCT04492306 - Clinical Evaluation of Dimethyl Sulfoxide Dentin Pre-treatment N/A
Recruiting NCT04141215 - Allogeneic Bone Paste Versus Allogeneic Bone Powder N/A
Recruiting NCT06182462 - Virtual Reality Distraction for Dental Anxiety (RCT) N/A
Enrolling by invitation NCT04894201 - Deep Learning to Summarize Findings in Dental Panoramic Radiographs
Not yet recruiting NCT05371535 - A Clinical Trial to Evaluate the Safety and Effectiveness of MatrixOssTM Bone Graft N/A
Enrolling by invitation NCT05022368 - Oral Device Clinical Trial Phase 1
Not yet recruiting NCT03103685 - Continue vs. Stop P2Y12 Inhibitor on Bleeding in Patient Receiving DAPT Undergoing Dental Procedure. Phase 4
Completed NCT05282212 - Point of Care, High Resolution and 3-Dimensional Ultrasonography
Completed NCT04686084 - Dual Energy Cone-Beam Computed Tomography (DE-CBCT) Assessment of Jaw Bone Density N/A
Completed NCT04657757 - Investigation of Bacterial Adhesion and Bactericide Effect ex Vivo on Different Implant Restoration Materials N/A
Not yet recruiting NCT06252935 - Effectiveness and Safety of Collagen Membrane (FormaAid®) in the Treatment of Periodontal Regeneration N/A