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Dental Caries clinical trials

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NCT ID: NCT00723515 Completed - Dental Caries Clinical Trials

Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study

Start date: February 2007
Phase: Phase 4
Study type: Interventional

The study hypothesis is the difference in therapeutic effect of two varnish formulations (G1 = NaF, 2.26%F, G2 = NaF, 2.71% F + CaF2). These products are commercially available in the Brazilian and international market and they are used for dental caries as white spot lesions control.

NCT ID: NCT00719238 Completed - Dental Caries Clinical Trials

A Pilot Study to Promote Maternal and Infant Oral Health

Start date: January 2007
Phase: N/A
Study type: Interventional

The long term goals of this project are to develop and implement a combined prenatal and postnatal intervention to decrease early childhood caries. The program is based on risk assessment, diet intervention and counseling. To accomplish these goals a pilot study is needed to determine: 1) The ability to recruit and retain pregnant mothers in an intervention program; 2) The levels of S. mutans in pregnant mothers; 3) The ability of a diet intervention to decrease S. mutans in pregnant mothers.

NCT ID: NCT00708305 Completed - Dental Caries Clinical Trials

Evaluation of Plaque Fluid Fluoride Retention From Fluoride Toothpastes

Start date: June 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the efficacy of different sodium fluoride (NaF) containing toothpastes in prevention of dental caries. Change from baseline fluoride data at various time points up to four hours after a single brushing with NaF containing toothpastes will be evaluated.

NCT ID: NCT00703001 Completed - Dental Caries Clinical Trials

Waukesha Smiles: Dental Outreach to Low-income Waukesha Children

Start date: April 2008
Phase: N/A
Study type: Interventional

The Waukesha Smiles Project will compare approaches to improve oral health habits and increase access to basic dental care for low-income children in Waukesha, Wisconsin through a school-based outreach program of oral health promotion, screening and referral.

NCT ID: NCT00674869 Completed - Caries, Dental Clinical Trials

Effectiveness of Pit and Fissure Sealants in the Prevention of Dental Caries

Start date: December 2004
Phase: N/A
Study type: Interventional

This randomized clinical trial is aimed at testing the efficacy of pit and fissure sealants, in a current environmental context different from that of the seventies and eighties. It has a split mouth design. 4OO subjects are included and the duration of follow up is 2 years.

NCT ID: NCT00658138 Completed - Dental Caries Clinical Trials

Clinical Evaluation of 3M™ ESPE™ Adper™ Scotchbond™ SE Self-Etch Adhesive in Class I and Class II Restorations in Adults

Start date: December 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the performance of a new dental adhesive system in the restoration of Class I and Class II cavities in adult teeth.

NCT ID: NCT00643461 Completed - Dental Caries Clinical Trials

Clinical Evaluation of Three Dental Adhesive Systems in Class V Restorations

Start date: April 2008
Phase: N/A
Study type: Observational

The purpose of this study is to compare the clinical performance of three dental adhesive systems used to bond Class V cavity fillings in adult teeth.

NCT ID: NCT00642252 Completed - Dental Caries Clinical Trials

Development and Validation of a Multi-Mineral Fluoride Mouthrinse

Start date: January 2012
Phase: Phase 1
Study type: Interventional

The primary goals of this project are to determine the anticaries benefits of a prototype multi-mineral mouthrinse containing 225 ppm fluoride and 30 ppm of a Ca through the remineralization of enamel white-spots (non-cavitated lesions). The selection of patients with pre-existing white-spot lesions will permit an opportunity to evaluate the efficacy of the multi-mineral mouthrinse in reminerzalizing and/or inhibiting progression of enamel white-spot lesions.

NCT ID: NCT00638677 Completed - Dental Caries Clinical Trials

Bifidobacterium Lactis BB12 and Xylitol Delivered With a Novel Slow-release Pacifier

Start date: June 2004
Phase: Phase 4
Study type: Interventional

Aims: 1. To develop a food supplement containing a health-promoting probiotic bacteria (B. lactis BB12) and xylitol to be administered with a novel soft, possibly occlusion-friendly pacifier. 2. Test in a clinical study how feasible the method is and to study how the intervention affects caries occurrence. Main hypothesis: The administration of B. lactis BB12 and xylitol affects beneficially the dental health of the child.

NCT ID: NCT00612469 Completed - Dental Caries Clinical Trials

The Use of Antimicrobial Agents in the Inhibition of Mutans Streptococci in Children With Dental Caries

Start date: October 2005
Phase: N/A
Study type: Interventional

The aim of the present study was to compare salivary MS levels in four different groups of children with caries, that have been submitted to intraoral topical treatment with either 1,23% sodium fluoride, 1% chlorhexidine, 3% or 10% vancomycin, during 6 consecutive days. This clinical trial was designed to test two different hypotheses. First, that topical vancomycin would be more effective than chlorhexidine and sodium fluoride in salivary MS reduction. Secondly, a 6-day antimicrobial treatment with either one of these agents would produce a long lasting MS suppression, dispensing repeated antibacterial treatments.