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Dental Caries clinical trials

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NCT ID: NCT01797458 Completed - Dental Caries Clinical Trials

European Study on Three Different Approaches to Managing Class 2 Cavities in Primary Teeth

Start date: May 2011
Phase: N/A
Study type: Interventional

The purpose of this randomized clinical trial is to compare the clinical effectiveness of three treatments involving different caries management strategies (conventional restorations, Hall technique, and Non-Restorative Caries Treatment) to the management of class II carious primary molars in children (3-8 year-old).

NCT ID: NCT01796106 Terminated - Caries,Dental Clinical Trials

Clinical Trial Proximal Caries Infiltration and Detection

Start date: March 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the clinical efficacy of resin infiltration (Icon, DMG, Germany) compared to fluoride varnish (Duraphat Fluoride Varnish, Colgate, USA) in the management of proximal early caries lesions in primary molars over 24 months. In addition, this study will assess the use of a scanning fiber endoscope (SFE) laser optical device for the assessment of caries lesions and their progression in comparison to radiographic examination. A total of 50 participants (age 6-13 years) with at least 1 proximal early caries lesion will be enrolled. The participants will be followed up at 12 and 24 months. Lesion status will be monitored through radiographic and SFE laser optical device imaging.

NCT ID: NCT01778699 Recruiting - Dental Caries Clinical Trials

Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2).

Start date: February 2013
Phase: Phase 4
Study type: Interventional

In a previous study the efficacy of Lb CD2 on interim covariates related to caries development was tested. So, it was decided to plan a new study on schoolchildren from the same area. The aim of the present research protocol was to evaluate the anticariogenic effect of probiotics daily used, on the caries development in children. The null hypothesis was that the probiotic Lb CD2 would not modify the caries risk of the children. Moreover, the study will be carried out to investigate the plaque acidogenicity in situ following the regular consumption of a probiotic product compared to a control group. Objective: To determine the effect of a regularly consumed probiotic on the development of new caries lesions. Study design: Double blind, placebo-controlled, longitudinal study, monocentric, national, in situ

NCT ID: NCT01768390 Completed - Dental Caries Clinical Trials

Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients

Start date: January 2008
Phase: Phase 4
Study type: Interventional

AIM: To evaluate the efficacy of daily tooth brushing with high concentrated fluoride dentifrice on white spot lesion (WSL) formation in adolescents during treatment with fixed orthodontic appliances (FOA). The null hypothesis is that neither incidence nor severity of lesions would differ from a control group using standard fluoride dentifrice. SUBJECTS AND METHODS: 420 healthy consecutive 11-16 year-old patients referred to 4 Orthodontic Specialist Clinics are randomized to use either a dentifrice containing 5.000 ppm fluoride or a regular dentifrice with 1.450 ppm sodium fluoride. To be eligible for inclusion, the patients are scheduled for bimaxillary treatment with FOA for an expected duration of at least 1 year. All are instructed to use 0.25 gram dentifrice and brush their teeth during 2 minutes twice daily during the entire period of treatment. Before bonding, and after polishing with a rubber cup and non-fluoride pumice paste, 3 digital photos of the maxillary incisors, canines and premolars are taken. At debonding, remaining composite material on the surfaces is removed with a slow rotating carbide bur followed by polishing with a rubber cup and pumice paste. A new series of frontal and lateral digital photos is thereafter exposed. The primary outcome measure is the incidence and severity of WSL as registered separately by two blinded experienced and calibrated clinicians according to a validated index. A random sample of 50 cases is re-assessed to check intra- and inter-examiner reliability. The intervention is indended run throughout the full duration of the orthodontic treatment, varying between 18 and 24 months.

NCT ID: NCT01763138 Completed - Dental Caries Clinical Trials

Effect of Educational Intervention in Mothers for Prevention of Caries in Their Children

Start date: June 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of an educational intervention on mothers knowledge, attitudes and practices for preventing childhood caries.

NCT ID: NCT01757990 Completed - Dental Caries Clinical Trials

The Effect of Stevia Rebaudiana Extracts on Different Variables Related to Caries: an in Vitro and in Vivo Evaluation.

Start date: March 2012
Phase: Phase 2
Study type: Interventional

The aim of the present investigation was to evaluate the effect of stevioside and rebaudioside on several variables related to caries development. Two approaches were performed: an in vitro evaluation of the growth of a culture of mutans streptococci and in vivo randomized study on the effect of a single rinse containing stevioside and rebaudioside on plaque-pH.

NCT ID: NCT01749267 Completed - Clinical trials for Dental Caries Extending Into Dentine

Digital Subtraction Radiography Evaluation of SMART Restoration With Partial Caries Removal in Primary Teeth

DSR
Start date: September 2010
Phase: N/A
Study type: Interventional

The objective of this study was to analyze the radiographic density of digital subtraction radiographs after SMART restoration with partial caries removal in primary molars at 6 and 12 months.

NCT ID: NCT01724827 Completed - Dental Caries Clinical Trials

Ceramic Versus Composite in the Treatment of Posterior Teeth by Inlays or Onlays

CECOIA
Start date: September 13, 2012
Phase: Phase 3
Study type: Interventional

The main purpose of this trial is to determine which material, between ceramic and composite, is best to manufacture dental inlays and onlays in the treatment of moderate dental substance losses, generally due to dental caries. Restorations will be done using direct Computer Assisted Design and Manufacturing (CAD-CAM). Another aim of this study is to determine which factors influence the success of these restorations.

NCT ID: NCT01720771 Completed - Dental Caries Clinical Trials

Preventive Effect of a Probiotic Tablet on Oral Health in Preschool Children

Start date: February 2013
Phase: N/A
Study type: Interventional

The aim of the prospective project is to investigate effect of daily probiotic supplements on dental caries development in preschool children living in a low socioeconomic immigrant area in souithern Sweden. The study design is a randomised controlled trial with two parallell arms. The intervention is one probiotic tablet or placebo once daily. The null hypothesis is that the caries experience and increment will not differ betwwen the two groups.

NCT ID: NCT01707797 Completed - Dental Caries Clinical Trials

Predicting Caries Risk in Underserved Toddlers in Primary Healthcare Settings

Start date: November 15, 2012
Phase:
Study type: Observational

The study aims to develop a questionnaire that can be used to help uncover a child's risk of developing dental caries (also known as tooth decay or a cavity). The aim is to develop a practical and easily-scored risk tool that a primary medical care provider can use to help find young children with the highest risk for developing cavities.