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Dental Caries clinical trials

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NCT ID: NCT06211582 Active, not recruiting - Caries,Dental Clinical Trials

Clinical Performances of 3-different Tooth-colored Restorative Materials in Class-II Cavities

Start date: September 15, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial comparatively investigate the clinical performances of 3 different tooth-colored restorative materials in the treatment of Class II cavities after 6 months and one year.

NCT ID: NCT06205459 Recruiting - Deep Caries Clinical Trials

Deep Marginal Acquisition With Thermacut Bur Vs. Functional Crown Lengthening in Deep Carious Lesions

Start date: February 2, 2024
Phase: N/A
Study type: Interventional

this clinical trial is conducted to compare between deep marginal acquistion by the means of thermacut bur Vs. functional crown lengthening in exposing deep subgingival interproximal cervical lesions

NCT ID: NCT06195449 Not yet recruiting - Tooth Decay Clinical Trials

Clinical and Radiographic Evaluation of Alkasite Restorative Material Versus Glass Ionomer Cement

GIC
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

To evaluate the clinical and radiographic performance of Alkasite restorative material versus glass ionomer in restoration of primary molars.

NCT ID: NCT06192667 Active, not recruiting - Caries,Dental Clinical Trials

Clinical Performance of Injectable Composite Resins in Class I Cavities

Start date: December 12, 2022
Phase: N/A
Study type: Interventional

Purpose of research: Evaluation and comparison of 24-month clinical performance of injectable and conventional resin composites in class I cavities.

NCT ID: NCT06187259 Completed - Clinical trials for Dental Caries in Children

Comparative Study Between Smart Bur II and Traditional Carbide Bur in Selective Removal of Caries in Permanent Molars

Start date: April 18, 2019
Phase: N/A
Study type: Interventional

A more biological and conservative technique of caries removal has emerged with minimally invasive restorative dentistry's advent. As a result, Smart Burs II has become a self-limiting, sensitive tool for removing caries. The current study aimed to validate and contrast the polymer burs' efficacy (Smart Burs II) versus conventional burs (Carbide burs) for infected carious dentin's selective removal in permanent first molars. Thirty permanent first molars fulfilling the inclusion criteria were chosen in 8-11 years old children with class I occlusal carious lesions. Group 1 (n=15) and Group 2 (n=15) were randomly assigned to have carious dentin removed utilizing standard carbide bur and a smart Bur II, consecutively. By employing caries detector dye, the effectiveness of caries removal was quantified as 0, 1, 2, 3, 4, or 5. The volume of removed carious tissue was recorded using impression material which was inserted into a calibrated insulin syringe. A statistically significant difference was discovered in the volume of removed carious tissue between both groups, while the efficiency of caries removal using either bur has no significant difference. Smart Bur II was more conservative in the carious dentin's removal than carbide bur. Smart Bur II was as efficient as carbide bur in caries removal.

NCT ID: NCT06182267 Completed - Caries,Dental Clinical Trials

Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101

Start date: November 27, 2023
Phase: Phase 1
Study type: Interventional

Pharmacokinetic (PK) study of L-arginine after exaggerated oral use of the novel dentifrice product COL101 after repeated daily applications in healthy adult subjects.

NCT ID: NCT06174194 Completed - Clinical trials for Dental Caries in Children

Effect of Sugar-Free Chewing Gum Containing Tulsi Extract on Salivary Streptococcus Mutans in a Group of Children

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial was to explore how adding Tulsi extract, a natural plant substance, to chewing gum affects the levels of Streptococcus mutans, type of bacteria that cause dental caries, in the saliva of children aged 4 to 11 years. Participants should not use removable prosthetics or orthodontic appliances and had had not used antibiotics in the 2 weeks preceding sample collection. We want to answer this main question: Can chewing gum with Tulsi extract significantly reduce the number of Streptococcus mutans bacteria in children's saliva? Participants tasks: - Children were asked to chew gum containing Tulsi extract for 5 minutes and then dispose of the gum. - Two salivary samples were collected from each child: one before gum chewing and another 30 minutes after disposing the gum. Researchers compared Streptococcus mutans counts in saliva before and after gum chewing to determine if there is a significant reduction in bacterial colonies.

NCT ID: NCT06172764 Recruiting - Dental Caries Clinical Trials

A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbiome

Incipient
Start date: December 12, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare the treatment effect of vitamin D supplementation and topical fluorides in the population having vitamin D deficiency and Initial Carious Lesions (ICL) on the progression of ICL in teeth. This study aims to observe the changes in the International Caries Detection and Assessment System (ICDAS) scores, the concentration of salivary proteins, and cariogenic microbes, six months after the interventions. - Group A will get vitamin D supplements and oral hygiene instructions (OHI). - Group B will get vitamin D supplements, topical fluorides, and OHI. - Group C (Control), the vitamin D sufficient group will get topical fluorides and OHI.

NCT ID: NCT06171776 Active, not recruiting - Deep Caries Clinical Trials

Evaluation of Conservative Management of Teeth With Deep Cavitated Carious Lesions

Start date: January 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this clinical trial is to compare postoperative pain of calcium silicate cement and resin-based tricalcium silicate (TheraCal LC) versus chemically Cured Glass Ionomer cement (FujiXI) in conservative management of very deep carious lesions by selective caries removal

NCT ID: NCT06169306 Not yet recruiting - Dental Caries Clinical Trials

Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.