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Dental Caries clinical trials

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NCT ID: NCT03963791 Not yet recruiting - Dental Caries Clinical Trials

Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP

REEPP-WSC
Start date: October 5, 2019
Phase: N/A
Study type: Interventional

This research is conducted to compare the remineralization efficacy of eggshell powder gel and CPP-ACP (MI paste) on post-orthodontic white spot lesions.

NCT ID: NCT03962634 Terminated - Clinical trials for Apical Periodontitis

Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Pediatric

Start date: August 28, 2019
Phase: Phase 2
Study type: Interventional

The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.

NCT ID: NCT03956992 Completed - Dental Caries Clinical Trials

Effects of a Hydroxyapatite-based Mouth Gel on Calcium Content of Plaque

Start date: August 8, 2019
Phase: N/A
Study type: Interventional

The aim of this pilot study is to analyze if a hydroxyapatite-containing mouth gel has an influence on the calcium content of plaque.

NCT ID: NCT03955341 Completed - Clinical trials for Patients With Deep Carious Lesions

Clinical Evaluation and Microbiological Assessment of Diode Laser and Chemical Disinfection in Comparison to Selective Caries Removal

Start date: October 20, 2019
Phase: N/A
Study type: Interventional

Objectives: To evaluate the clinical and antimicrobial effect of Diode laser and chemical disinfection in comparison to selective caries removal in management of deep carious lesions. Methods: This study will be carried on 30 patients with an age range of 18 -50 years. The patients will be selected from the outpatient clinics in Faculty of Oral and Dental Medicine, Misr International University. All patients will be randomly divided into 3 equal groups; Control group, Diode laser application with an output power of 0.5 watt group, and Chemical disinfection group. Preoperative clinical assessment and radiographs will be performed before intervention and then the patients will receive their treatment and final restorations. Follow-up with clinical assessments will be performed after 3 and 6 months. Cone beam computed tomography will be performed at the day of intervention and after 6 months. Clinical, Microbiological and Radiographic data will be collected, tabulated and statistically analyzed to compare between the success rates of diode laser, chemical disinfection and conventional selective caries removal.

NCT ID: NCT03930927 Not yet recruiting - Clinical trials for White Spot Lesion of Tooth

Effect of Self Assembling Peptide on White Spot Lesion

regeneration
Start date: May 1, 2019
Phase: Early Phase 1
Study type: Interventional

During re-mineralization of white spot lesion, Will biomimetic self-assembling peptides improve the re-mineralizating effect of the post orthodontic white spot lesion compared to fluoride-based delivery systems?

NCT ID: NCT03928587 Completed - Dental Caries Clinical Trials

Effect of 12 Months Supplementation With a Symbiotic Lozenge on Caries Increment in Healthy Children

PiP-C
Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The primary objective of this trial is to investigate the effect of a symbiotic lozenge on dental caries in young children.

NCT ID: NCT03923192 Completed - Clinical trials for Proximal Dental Caries

Evaluation of Reliability of the Near-infrared Imaging System (VistaCam iX Proxi) in Comparison With Digital Radiographic Findings and ICDAS-II in Detection of Approximal Carious Lesions.

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the Clinical performance of the near-infrared imaging system VistaCam iX Proxi in comparison with digital radiographic findings and ICDAS-II in detection of approximal carious lesions.

NCT ID: NCT03921307 Completed - Dental Caries Clinical Trials

Clinical Performance of Ceramic CAD/CAM Crowns

Start date: May 15, 2017
Phase:
Study type: Observational

The purpose of this study was to evaluate the clinical performance of laboratory and chairside fabricated monolithic anterior and posterior LDGC CAD/CAM crowns performed by predoctoral students at the University of Toronto and the effect of different patient and provider-related factors on their longevity and to compare them to the metal-ceramic (MC) crowns. A sample of LDGC CAD/CAM crowns (IPS e.max, Ivoclar Vivadent) provided by predoctoral students was evaluated. Crown preparations were made according to the specific criteria and were milled in-house using the CEREC bluecam and Omnicam systems. Crowns were cemented with Rely-X Unicem (3M/ESPE) and Calibra Universal (Dentsply Sirona) resin cements. Clinical assessment of the crowns and supporting periodontal structures was performed following the modified California Dental Association (CDA) criteria. Intra-oral photographs, periapical and bitewing radiographs were taken for further assessment by two evaluators. Two-hundred and fifty-one patients with 275 crowns were examined with a follow-up period of up to 6 years.

NCT ID: NCT03916926 Active, not recruiting - Dental Caries Clinical Trials

Older Adult Effectiveness of 2 Treatments

Start date: September 18, 2019
Phase: N/A
Study type: Interventional

The study is a cluster randomized clinical trial (RCT) to be conducted in 22 publicly subsidized housing facilities/sites (HUD Section 202) and other low-income housing voucher programs in NE Ohio. The facilities will be randomized to 2 arms: Arm 1 (11 sites) - Participants will receive biannual silver diamine fluoride (SDF) versus Arm 2 (11 sites): Participants will receive atraumatic restorative treatment (ART) with glass ionomer cement (GIC) + biannual fluoride varnish (FV) application. A total of 550 participants (Arm 1: 275, Arm 2: 275) will be followed for one year (baseline, 26 weeks, 52 weeks). The protocol for each arm will address both coronal and root surface tooth decay lesions: Arm 1: The treatment will be bi-annual topical 38% SDF(Advantage Arrest, Elevate Oral Care LLC., West Palm Beach, FL) following manufacturer's instructions and published guidelines; Arm 2: The treatment will be ART will be a modification where the cavity will be restored with high viscosity glass-ionomer cement (GIC) (GC Fuji Automix LC Resin Reinforced Glass Ionomer Restorative, Japan)). Patients will also receive biannual topical fluoride varnish treatments (FluoriMax, Elevate) according to manufacturer's instructions.

NCT ID: NCT03889535 Completed - Caries, Dental Clinical Trials

Anterior Zirconia vs. Resin Strip Crowns

Start date: April 11, 2019
Phase: N/A
Study type: Interventional

This study is comparing the effectiveness of two different dental crown fillings (resin crowns and zirconia crowns) for primary front teeth (incisors). Both dental crown fillings are currently used by community pediatric dentists. Resin crowns are currently the standard treatment for primary incisors at The Hospital for Sick Children (SickKids). Zirconia crowns are not presently used at SickKids. It is unknown if one type of crown is better than the other type. If the zirconia crowns produce similar or better results in fixing the primary front teeth, then the zirconia crowns may become the new standard of care at SickKids.