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Dental Caries clinical trials

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NCT ID: NCT05959382 Completed - Dental Caries Clinical Trials

Evaluation of Clinical Success of Restorations Using Different Magnification Aids

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

This study aimed to investigate the effect of using a loupe and dental operating microscope with different magnifications on the success of class II direct composite restorations.

NCT ID: NCT05946473 Not yet recruiting - Dental Caries Clinical Trials

Development of a Novel Anti-caries Chewing Gum

Start date: July 2023
Phase: N/A
Study type: Interventional

This research study is designed to evaluate the chewing gum's ability to modulate the oral microbiome in human participants, in addition to its safety.

NCT ID: NCT05943782 Not yet recruiting - Caries,Dental Clinical Trials

Evaluation of CAD/CAM Onlays Fabricated by Subtractive Versus Additive Digital Manufacturing Techniques.

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Aim of the study: The aim of this RCT is to evaluate CAD/CAM onlays fabricated by subtractive technique (brilliant crios) versus additive technique (varseosmile crown plus material), in terms of clinical functional evaluation following the FDI criteria and three-dimensional digital evaluation of the marginal and internal fit by triple scan protocol. Materials and methods: A total of 30 patients will be enrolled in the clinical trial following the eligibility criteria. Then, the patients will be randomly allocated to receive either 3D printed onlays or milled ones. A blinded operator will prepare a standardized cavity for the restoration and an impression will be performed. After designing the restoration on the Exocad software, A dentist not involved in the clinical part of the study will receive the STL file of the design and envelopes containing the information necessary only to manufacture the restorations (tooth numbers and restorative materials) to proceed with either the milling or printing procedures. Try in and cementation procedures will be similarly performed for both groups by a blinded operator. Finally, the marginal and internal fit will be evaluated by using the triple scan protocol for digital 3D assessment. Also, a baseline, six months and 12 months assessments will be performed by a blinded examiner, not involved in the clinical part for assessing the functional clinical performance of the re3stprations using the FDI criteria. Finally, the data will be statistically analyzed.

NCT ID: NCT05941429 Not yet recruiting - Clinical trials for Dental Caries in Children

Comparison of Cariostatic Effect of Nano-Silver Fluoride Versus Silver Diamine Fluoride

Start date: August 2023
Phase: Phase 1
Study type: Interventional

This study will be conducted to test the cariostatic effect of Nano Silver Fluoride in a comparison to Silver Diamine Fluoride in a group of preschool children.

NCT ID: NCT05935813 Active, not recruiting - Caries,Dental Clinical Trials

Caries in Adolescents (Karies Hos Ungdom)

Start date: January 1, 2008
Phase:
Study type: Observational

In this study the objective is to establish in depth knowledge about adolescents' oral health characteristics, - practices and - needs. Further, we want to evaluate whether adolescents' caries status can be associated with existing socio-economic inequality, emotional health and lifestyle factors. The main question[s] it aims to answer are: 1. What is the caries status (i.e. prevalence, increment at different timepoints and characteristics) among adolescents in Trøndelag? - What is the caries prevalence in different age groups? - Is there any difference in caries prevalence linked to specific age groups, gender or urban versus rural areas? - Are approximal tooth surfaces especially prone to the development of new caries lesions? - Is the caries increment from 12 to 20 years a continuous process or are there high-risk periods within this timespan? - How is the prevalence of enamel caries? Is enamel caries more prevalent in younger age groups than in older age groups? 2. What are the patterns of recall intervals and non-attendance in different age groups, among adolescents in Trøndelag? - What are the attendance rates and prevalence of non-attendance at dental appointments in different age groups? - What is the recall interval between regular follow-up dental visits? - Are there any recall or attendance characteristics linked to age group, gender or urban versus rural areas? 3. What factors (i.e. oral health behaviours, socioeconomic-, lifestyle- and parental factors) are associated with caries among Norwegian adolescents? - How are the oral health behaviours (i.e. dietary- and oral hygiene habits, attendance to dental care) among adolescents, and are there any shared oral health behavioural challenges? - Is the caries prevalence linked to life challenges (mental illness, alcohol/drug use and chronic diseases)? - To what degree are oral health behaviours associated with caries among adolescents? - Is there any association between media screen time and oral health behaviours, and cariesstatus? - Is there any association between physical activity, sport participation and oral health behaviours, and caries status? - What are the associations between socioeconomic factors (study program, birth- and migration background, and parental income, education and employment) and oral health behaviours, and caries status? For research question 1 and 2, the sample will be adolescents aged 12-20 years living in Trøndelag county in the time period 2008-2020, (n≈115000, Statistics Norway, SSB). Data will be extracted from dental health records in the public dental service (Den offentlige tannhelsetjenesten, Trøndelag Fylkeskommune). The public dental service annually reports caries prevalence for 12- and 18-year-olds, Statistics Norway, SSB (Figure 1). However, the knowledge is modest about the caries development within the six years from 12 to 18 years of age. Further, the public dental service offers subsidised dental care to 19- and 20-year-olds. Extracting data from dental health records in the public dental service will give us the opportunity to explore the caries increment at multiple timepoints, and attendance rates at dental appointments throughout the teenage period from 12 to 20 years of age. For research question 3, the sample will be adolescents (n≈8000) and their parents that participated in the fourth survey of The Trøndelag Health Study (HUNT4) in 2017-2019. Self-reported questionnaire data will be linked to data from dental health records in the public dental service.

NCT ID: NCT05931705 Completed - Vitamin D Status Clinical Trials

Vit D Receptor Gene Polymorphism

VITAMIN D GENE
Start date: March 1, 2022
Phase:
Study type: Observational

The present cross-sectional observational study was conducted after the university ethical committee approved the research (NU/CEC/2020/0339). This study included 376 adults in the age group of 18-40Yrs. The patient information sheet briefed the study details and usage of salivary samples. Informed consent was obtained from participants. Healthy individuals free of associated systemic conditions, individuals not under any nutritional supplementation were included in the study, and lactating mothers, smokers, and menopausal women were excluded

NCT ID: NCT05919576 Completed - Caries,Dental Clinical Trials

Near Infrared Technology for the Detection of Proximal Caries

Start date: August 8, 2022
Phase:
Study type: Observational

This study aims to determine the effectiveness of an intraoral scanner with near-infrared imaging (NIRI) for the diagnosis of proximal caries.

NCT ID: NCT05913258 Completed - Dental Caries Clinical Trials

Caries Removal in Primary Teeth Using Er:YAG Laser

Start date: January 1, 2020
Phase: Phase 3
Study type: Interventional

Objective: To assess and compare the 2940 nm erbium:yttrium-aluminum-garnet (Er:YAG) laser versus a conventional rotary treatment during cavity preparation in children with regard to anxiety level, pain perception, restoration integrity, and bond interface quality. Materials and Methods: In a randomized, blinded trial using a split-mouth design, forty (9-12-year-old) children with 80 carious deciduous molars were included. The cavity in one quadrant was treated conventionally using a bur, while the cavity in the other quadrant was prepared using an Er:YAG laser. Venham's dental anxiety scale and pulse rate measurement using a fingertip pulse oximeter were used to evaluate dental anxiety levels. The Wong-Baker facial pain rating scale and the number of local anesthesia required during both interventions were further applied to investigate pain perception. At the 1-year follow-up, clinical examinations was conducted and the integrity of the restorations was clinically assessed according to the Ryge criteria. Lastly, the restored teeth were extracted and histologically evaluated for bond interface quality using scanning electronic microscopy.

NCT ID: NCT05910905 Not yet recruiting - Carious Teeth Clinical Trials

Clinical Efficacy of Preformed Pediatric Zirconia and Metal Crown

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

The study was planned to evaluate and compare the clinical success of prefabricated stainless steel crowns and zirconia crowns used in the primary molars. The study will be carried out in healthy children aged 6-9 years with caries on more than one surface of the primary molars.

NCT ID: NCT05910645 Recruiting - Dental Caries Clinical Trials

Knowledge, Attitude and Practice Regarding Caries Risk Assessment for Children and Adults Among Dental Residents

Start date: October 2023
Phase:
Study type: Observational

Evaluation of knowledge, practice and attitude regarding Caries Risk Assessment for children and adults among Dental Residents in Faculty of Dentistry, Cairo University.