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Dental Caries in Children clinical trials

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NCT ID: NCT05875064 Not yet recruiting - Clinical trials for Dental Caries in Children

Aesthetic Restorations in Deciduous Anterior Teeth

Start date: August 1, 2023
Phase: Phase 3
Study type: Interventional

This study proposes to conduct a randomized clinical trial (RCT), composed of a sample of 194 deciduous central and lateral incisors with active cavitated lesions, simplified ICDAS C+ score, with involvement of more than two surfaces. This sample will be divided into two experimental groups, both with selective removal of carious tissue: a group in which conventional restoration will be performed using opaque resins; and another group with monochromatic resin with chameleon effect and polyvinyl crowns.

NCT ID: NCT05872542 Recruiting - Clinical trials for Dental Caries in Children

SDF Effectiveness on Arresting Caries in Children

Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

Purpose: To assess the clinical effectiveness of silver diamine fluoride (SDF) to control asymptomatic cavitated carious lesions compared to conventional glass ionomer restoration in preschool children.

NCT ID: NCT05839548 Not yet recruiting - Clinical trials for Dental Caries in Children

Articaine Efficacy and Safety for 3 Years Old Children

Start date: June 1, 2023
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to determine the local anesthetic efficacy and safety of 4% Articaine compared 2% Mepivicaine in 3 years old children, by using infiltration technique for primary teeth that required restorative, pulp therapy, or dental extraction procedure, as assessed by measuring the pain experience during injection and treatment procedures, child's behavior during the procedure, and postoperative complications.

NCT ID: NCT05829304 Not yet recruiting - Clinical trials for Dental Caries in Children

A Comparative Clinical and Radiographic Study Of Collagen Based Pulpotomy in Cariously Exposed Vital Primary Molars

Start date: June 2023
Phase: N/A
Study type: Interventional

To assess post operative pain and survival rate after collagen based pulpotomy versus MTA pulpotomy in children with vital primary molars.

NCT ID: NCT05772039 Enrolling by invitation - Quality of Life Clinical Trials

Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life

Start date: January 18, 2022
Phase: Phase 4
Study type: Interventional

There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on non-restorative treatments for cavitated carious lesions advocate the use of silver diammine fluoride biannually for high caries risk patients

NCT ID: NCT05670743 Active, not recruiting - Clinical trials for Dental Caries in Children

Pharmacokinetics of Advantage Arrest in Healthy Children 13-Months to 13-Years of Age

Start date: March 1, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to further characterize basic pharmacokinetic (PK) parameters in healthy children to contribute to evidence for the safety of silver diamine fluoride (SDF; Advantage Arrest). Children with at least one active cavity will be treated and then have blood draws at random time points afterwards.

NCT ID: NCT05652231 Completed - Clinical trials for Dental Caries in Children

Assessment of Dental Caries Among a Group of Institutionalized Orphan Children Compared to Parented School Children

Start date: November 1, 2022
Phase:
Study type: Observational [Patient Registry]

Children from two orphanages will be examined for dental caries experience, in comparison to parented school children.

NCT ID: NCT05645029 Completed - Clinical trials for Dental Caries in Children

Evaluation of Glass Ionomer Cement Modified With Chlorhexidine and Titanium Dioxide in Primary Molars (RCT)

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

to investigate the effect of modifying GIC with different formulations on the antibacterial activity and clinical performance in reference to unmodified glass ionomer restorative materials.

NCT ID: NCT05638217 Completed - Clinical trials for Dental Caries in Children

Efficacy of the Use of Silver Diamine Fluoride and Sodium Fluoride Varnish for the Treatment of Caries in Children

Start date: November 7, 2022
Phase:
Study type: Observational

The goal of this observational study is to identify the efficacy of silver diamine fluoride 38% followed by sodium fluoride varnish 5% in a population with untreated dental caries age range 4 to 12 years old. The main questions to answer are - Efficacy of treatment of active tooth decay with the treatment protocol of 38% silver diamine fluoride and 5% sodium fluoride varnish. - Clinical evaluation of tooth decay treated with 38% silver diamine fluoride and 5% sodium fluoride varnish in quality of hardness, color change and caries progression. - Explore the association of treatment with 38% silver diamine fluoride and 5% sodium fluoride varnish with: i. Reduction of oral pain caused by the presence of carious lesions. ii. Improvement in gingival oral health. iii. Changes in general nutritional status through measurements of height, weight, hemoglobin levels and nutritional survey. The participants will be identified, charted (with nutritional surveys and parameters), as well as treated and compared in a six- and twelve-month period, where researchers will clinically identify the association between the use of this protocol and the efficacy of such, as well as other related nutritional aspects.

NCT ID: NCT05623605 Recruiting - Clinical trials for Dental Caries in Children

Evaluation of New Different Herbal Mouthwashes Against Caries Forming Bacteria, RCT

Start date: June 19, 2022
Phase: Phase 4
Study type: Interventional

The goal of this randomized controlled trial is to compare three different types of mouthwash, Moringa, Star anis, and Indian Costus 90 children participated in this study divided into 3 groups according to the type of mouthwash used and then subdivided in each group into 3 subgroups according to the concentration of the mouthwash 5,10,15%. the children were asked to rinse with the mouthwash 3 times per day for 1 week. bacterial count for streptococcus mutans was measured before and after the use of mouthwash to see the most effective concentration.