The Effect of Conscious Sedation on Acute Stress

Status Completed

Clinical Trial Summary

The specific aims of the present study were to evaluate sAA responses to impacted third molar extractions at different time points in the patients under conscious sedation with local anesthesia and to examine the relationship between sAA, conscious sedation and dental anxiety. The null hypothesis was that conscious sedation could be considered to reduce salivary alpha amylase level during the wisdom tooth surgery.

Clinical Trial Description

In oral and maxillofacial surgery, surgical extraction of impacted third molars is one of the most common surgical techniques performed in the oral cavity. Conscious intravenous sedation could be administered for the patients to provide anxiolysis, sedation, and analgesia for the patient. Salivary alpha-amylase (sAA) which reflect stress-related changes in the autonomic nervous system (ANS), has been proposed as a non-invasive stress biomarker. The aim of the present study was to investigate whether salivary alpha amylase (sAA) levels could be decreased by conscious sedation in the patients undergoing impacted third molar extraction. A total of 18 male patients were recruited. All patients were administered Modified Dental Anxiety Scale (MDAS) test. Patients were divided into two groups: test group (procedures under sedation) and control group (procedures under local anesthesia). The following parameters were monitored at different study time-points: systolic blood pressure (SBP), diastolic blood pressure (DBP), oxygen saturation (SO2), and heart rate (HR). Five samples of saliva were taken from each patient: the first time patient came to clinic, the patient sat in the chair for extraction, before local anesthesia, immediately after extraction, at 4 h after extraction. The concentrations of sAA were measured and compared across the different stages of the study between two groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04207515
Study type	Interventional
Source	University of Beykent
Contact
Status	Completed
Phase	N/A
Start date	April 15, 2018
Completion date	September 20, 2019

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT06385314` - A Cross Sectional Study on Dental Anxiety and State Anxiety Related to Removal of Fixed Partial Dentures
Completed	`NCT04308005` - Drawing as a Measurement of Dental Anxiety
Completed	`NCT01908127` - Efficacy of Film Modelling in Paediatric Dentistry	N/A
Completed	`NCT00695630` - Flumazenil Reversal of Oral Triazolam	Phase 1/Phase 2
Completed	`NCT05759286` - A Blend of Lavender-neroli Oils Aromatherapy and Music for Managing Anxiety in a Pediatric Patient	N/A
Completed	`NCT04234737` - Efficacy of Hypnotherapy in Children With Dental Anxiety	N/A
Completed	`NCT03838081` - Evaluation on the Anxiety of Third Molar Extraction	N/A
Enrolling by invitation	`NCT06057090` - Do Therapy Dogs Improve Behavior and Reduce Anxiety in Pediatric Dental Patients?	N/A
Not yet recruiting	`NCT04924452` - Er:YAG Laser Therapy in Combination With Behaviour Management Technique in Reducing Anxiety Among Paediatric Patients	N/A
Completed	`NCT03722771` - Influence of Lavender Oil on Vital Signs in Oral Surgery Patients	N/A
Completed	`NCT03596255` - Clinical Estimation of Dental Anxiety
Completed	`NCT05038540` - The Effect of Virtual Reality Glasses on Dental Anxiety Control	N/A
Completed	`NCT03324347` - Dog-Assisted Therapy in Dentistry	N/A
Not yet recruiting	`NCT06139640` - The Effect of Damask Rose Essential Oil Aromatherapy on Dental Anxiety and Pain on Children	N/A
Completed	`NCT02588079` - Internet-Based Cognitive Behavioral Therapy for Children With Dental Anxiety	N/A
Completed	`NCT02591797` - Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children	N/A
Not yet recruiting	`NCT00355693` - Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Anxious Patients	Phase 4
Recruiting	`NCT06243705` - Effectiveness of Robot-pets in Reducing Dental Anxiety in Children	N/A
Recruiting	`NCT06058533` - Pre-Visit Positive Imagery in Reducing Dental Anxiety	N/A
Completed	`NCT03993080` - Virtual Reality Relaxation to Decrease Dental Anxiety	N/A