Dengue Fever Clinical Trial
Official title:
Role of Andi-d in Dengue Fever: a Pilot Study
The purpose of this study is evaluate the role of anti-d in dengue fever.
This study was conducted in pgimer. Patients presenting with fever and thrombocytopenia in
emergency medical opd / medicine opd were screened and all dengue serology positive patients
were evaluated for enrolment into the study. We had proposed to enroll 30 patients with
diagnosed dengue haemorrhagic fever. the diagnosis of the dengue fever was based upon the
clinical history ,general physical examination and the lab tests : thrombocytopenia (
platelet count ≤ 20,000 ) ,and a positive dengue serology.
STUDY DESIGN : It was an open label inteventional study . one group of 15 patients (
intervention group ) received platelet support along with injection anti-d in a dose of 50
µg/kg (250IU/kg) intravenously while the other group of 15 ( control group) received
platelet support only . a base line platelet count of all the participant of both the study
groups was taken and then the level of platelets at 12 , 24 , 36 , and 48hr post treatment
initiation was noted. The patients were followed till the time of discharge .
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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