Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Change from baseline in Brief Assessment of Social Skills-Dementia (BASS-D) |
A screening test of social cognition in neurodegeneration |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Picture Interpretation Test (PIT) |
A test of executive functions |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Verbal Reasoning Test (VRT-A) - Absurdity sub-test |
A test of verbal reasoning |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Brief Executive Language Screen (BELS) |
A language test |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Bamberg Dementia Screening Test (BDST) |
A test of global cognitive efficiency |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Testament Definition Scale (TDS) |
A scale to assess testament representation |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Testamentary Capacity Assessment Tool (TCAT) |
A test to assess cognitive functions (i.e., memory, executive functions, social cognition, and numerical abilities) at the base of testamentary capacity |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Telephone Interview for Cognitive Status (TICS) |
A telephone-based screening test of global cognitive efficiency |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Telephone-based Mini-Mental State Examination (I-TEL-MMSE) |
A telephone-based screening test of global cognitive efficiency |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Telephone-based Global Examination of Mental State (tele-GEMS) |
A telephone-based screening test of global cognitive efficiency |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Telephone-based Amyotrophic Lateral Sclerosis Cognitive Behavioural Screen (ALS-CBS™-PhV |
A telephone-based screening test for cognitive functions in ALS |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Telephone-based Frontal Assessment Battery (t-FAB) |
A telephone-based screening test of executive functions |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Development of the Bizzare Pictures Test (BPT) |
A new visual test to assess reasoning abilities |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|
Primary |
Change from baseline in Development Telephone Language Screener (TLS) |
A new telephone-based test to asses linguistic functions |
At baseline (i.e., at the enrollment; all participants); after 1 month (for test-retest analyses in neurologically healthy individuals); after 6, 12, and 18 months in participants with neurodegenerative disorders |
|