Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Other |
Blood pressure, mmHg. |
Systolic and diastolic blood pressure |
One assessment within 8 weeks from consent |
|
Other |
BMI, kg/m2 |
Body mass index |
One assessment within 8 weeks from consent |
|
Other |
Waist-hip ratio, cm. |
Hip-waist Circumference: measured to nearest 0.1cm |
One assessment within 8 weeks from consent |
|
Other |
Blood glucose, mmol/L |
Fasting Glucose |
One assessment within 8 weeks from consent |
|
Other |
Glycated hemoglobin, mmol/mol |
Blood level of glycated haemoglobin A1c (HbA1c) |
One assessment within 8 weeks from consent |
|
Other |
Cholesterol, mmol/L |
Total blood cholesterol level |
One assessment within 8 weeks from consent |
|
Other |
LDL cholesterol, mmol/L |
Blood low density lipoprotein cholesterol level |
One assessment within 8 weeks from consent |
|
Other |
HDL, mmol/L |
Blood high density lipoprotein cholesterol level |
One assessment within 8 weeks from consent |
|
Other |
Triglycerides, mmol/L |
Blood triglycerides level |
One assessment within 8 weeks from consent |
|
Other |
Creatinine, mg/dl |
Blood creatinine level |
One assessment within 8 weeks from consent |
|
Other |
CRP, mg/L |
Blood C-reactive protein level |
One assessment within 8 weeks from consent |
|
Other |
Smoking habits |
Self-reported questions about smoking status: never/past/current |
One assessment within 8 weeks from consent |
|
Other |
Current medications |
Self-reported list of medication currently used |
One assessment within 8 weeks from consent |
|
Other |
Medical history |
Diagnoses, hospitalizations and other relevant events related to the participants healthcare will be recorded from national registers |
Through study completion, an average of 2 years |
|
Other |
Sociodemographic factors |
Marital status, living/domicile setting, current yearly income, work history. |
One assessment within 8 weeks from consent |
|
Other |
Leisure activities |
Self-reported questions inquiring about 12 leisure-time activities. |
One assessment within 8 weeks from consent |
|
Primary |
Cognitive performance, CERAD |
Finnish version of CERAD (Consortium to Establish a Registry for Alzheimer´s Disease). Score range: 0-100, higher score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Primary |
Cognitive performance, MMSE |
Mini Mental State Examination. Score range: 0-30, higher score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Primary |
Clinical Dementia Rating, units on a scale. |
Influence of cognitive impairment on the ability to conduct everyday activities on six domains (memory, orientation, judgment and problem solving, community affairs, home and hobbies, and personal care). Score ranges: 0-3 (individual domain), 0-18 (total score as sum of the six domains). Lower score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Primary |
Activity of Daily Living, Katz Index. |
Self-reported questionnaire ranking the independence in six basic daily functions. For each activity, the participant is rated either dependent (0 points) or independent (1 point). The total score score ranges 0-6 and a higher score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Primary |
Activity of Daily Living, Lawton-Brody Scale. |
Self-reported questionnaire assessing the level of functioning in eight daily activities necessary for living in the community. For each activity, the participant is rated either dependent (0 points) or independent (1 point). Score ranges 0-8 and a higher score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Primary |
Dementia and mild cognitive impairment |
MCI and dementia diagnoses (including type of dementia) will be ascertained from the participants' medical records. Data linkage to national registers. |
Through study completion, an average of 2 years |
|
Secondary |
Multimorbidity |
Total number of diagnoses of concomitant chronic medical conditions ascertained based on medical history data from e.g. previous follow-up data, as well as medical records. Data linkage to national registers. |
Through study completion, an average of 2 years |
|
Secondary |
Frailty Index, units on a scale. |
Fried Frailty phenotype, defined by assessing five criteria: unintentional weight loss, self-reported exhaustion, weakness by grip strength, slow walking speed, and low physical activity. One point is attributed when each of the five criteria is met. Score range: 0-5, a lower score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Secondary |
Short Physical Performance Battery, units on a scale. |
Physical performance is assessed in three domains: balance standing (score range: 0-4), chair standing (score range: 0-4), and gait speed (score range: 0-4). The total score (range: 0-12) is the sum of the three scores. A higher score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Secondary |
Physical functioning - Hand-grip strength, kg. |
The test measures the maximum isometric strength of the hand and forearm muscles and it is carried out with the aid of a hand-grip dynamometer. |
One assessment within 8 weeks from consent |
|
Secondary |
Self-reported physical activity |
Number of days/week in which physical activity is carried out for at least 20 minutes. |
One assessment within 8 weeks from consent |
|
Secondary |
Psychosocial wellbeing - Hopelessness, units on a scale. |
Self-reported questions inquiring about sense of hopelessness. |
One assessment within 8 weeks from consent |
|
Secondary |
Psychosocial wellbeing - Social network |
Self-reported questions inquiring about social network. |
One assessment within 8 weeks from consent |
|
Secondary |
Psychosocial wellbeing - Subjective memory complaints, units on a scale. |
22-item self-reported questionnaire inquiring on subjective memory. Score range: 0-66, a lower score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Secondary |
Psychosocial wellbeing - Anxiety, units on a scale |
State Trait Anxiety Inventory (STAI -6), self-reported 6-item questionnaire inquiring about sense of anxiety. Score range: 0-18, a lower score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Secondary |
Psychosocial wellbeing - Depression, units on a scale. |
Beck Depression Inventory (BDI), a 21-item self-reported questionnaire including inquiring about symptoms of depression. Score range: 0-63. A lower score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Secondary |
Psychosocial wellbeing - Life events |
Self-reported list of 12 significant life events. |
One assessment within 8 weeks from consent |
|
Secondary |
Psychosocial wellbeing - Sleep quality, units on a scale. |
Pittsburgh Sleep Quality Index (PSQI), measuring the quality and patterns of sleep in older adults. Score range 0-21. A lower score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Secondary |
Oral health |
Self-reported questions inquiring about oral health. |
One assessment within 8 weeks from consent |
|
Secondary |
Nutritional status, units on a scale. |
Mini Nutritional Assessment (MNA), a screening tool specifically designed for older adults to help identify elderly people who are malnourished or at risk of malnutrition. The assessment consists of six items evaluated by the assessor. A score (0-3 or 0-2) is attributed to each item based on the assessor's evaluation. The overall score ranges 0-14, and a higher score indicates a better outcome. |
One assessment within 8 weeks from consent |
|
Secondary |
Dietary habits |
Self-reported questions inquiring about dietary habits. |
One assessment within 8 weeks from consent |
|
Secondary |
Health-related quality of life, units on a scale. |
RAND 36-Item Health Survey 1.0, a 36-item self-reported questionnaire inquiring about health related quality of life. Score range: 0-100, a higher score indicates a better outcome. |
One assessment within 8 weeks from consent |
|