Clinical Trials Logo

Clinical Trial Summary

Post-extubation dysphagia (PED) is a frequent but still underestimated condition in the intensive care units (ICU). In the international literature, the manifestations and consequences of PED lead to intra- and post-intensive care comorbidities. The exact etiology of PED is unknown, but considered multifactorial. Numerous causes, acquired during ICU, can lead to a delay in the reintroduction of intravenous nutrition, or even favor the development of inhalation pneumopathy. One of these causes is the presence of the nasogastric tube. The incidence of ECD varies from 3 to 62%. Its presence impacts morbidity and mortality. Preventive strategies for PED have only been studied with questionable methodologies. The goal of ICU therapists is to detect PED as early as possible in order to implement curative strategies such as adapted nutrition and early swallowing rehabilitation.


Clinical Trial Description

There are several tools available to diagnose PED. These assessment methods are numerous and not subject to consensus. There are expensive instrumental methods requiring experts, which allow for accurate diagnosis but cannot be routinely used at the ICU patient's bed. For the ICU patient, bed-side clinical assessments seem more appropriate. The "Yale swallow protocol" (YSP), is the most used test in the literature. Its sensitivity in predicting PED at 96.5%, a negative predictive value of 97.9% and a false negative rate of less than 2%, seem to make it the most suitable. Currently, no recommendations have been made by French or international ICU societies on the appropriate time or method for PED assessment. Regarding the treatment of PED, the literature shows that physiotherapy management would not significantly reduce its incidence, nor accelerate the resumption of per os feeding. No study has examined the impact of nasogastric tube removal combined with the use of a standardized swallow test on post-extubation ECD. For all these reasons, we plan to evaluate the interventional strategy consisting in removing the nasogastric feeding tube as soon as extubation, to carry out between 1 hour and 6 hours post extubation the "Yale swallow protocol", to allow a resumption of feeding as soon as possible while screening the dysphagic patients. The research hypothesis is therefore: "Systematic removal of the nasogastric tube during the extubation procedure associated with an early swallow test in the ICU allows an early per-os nutritional resumption in comparison with the classical strategy of nasogastric tube management and swallowing disorders assessment" ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05795569
Study type Interventional
Source Centre Hospitalier Régional d'Orléans
Contact Aurelie DESPUJOLS
Phone +33238744071
Email aurelie.despujols@chr-orleans.fr
Status Recruiting
Phase N/A
Start date March 21, 2023
Completion date April 2025

See also
  Status Clinical Trial Phase
Not yet recruiting NCT06445309 - Design and Development of a Functional Plant-based Beverage Formulated According to the Main Nutritional Guides for Early Elderly Requirements to Improve Nutritional Status and Immunity for the Early Elderly People to Get Well-healthy Ageing
Completed NCT00570557 - Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia N/A
Completed NCT04243577 - Wearable Monitoring Systems for Swallowing Function and Disorders Early Phase 1
Recruiting NCT03975465 - EMST and Swallowing in Long-Term Survivors of HNCA N/A
Completed NCT05013918 - Oral Health and Nutrition Integrated Care Model
Recruiting NCT05439447 - A Study on Building a Voice Cohort for the Development of a Non-face-to-face Machine Learning Diagnostic and Monitoring Platform Using Voice Analysis and Various Sensors in Patients With Dysphagia.
Recruiting NCT05149976 - Establishment of Voice Analysis Cohort for Development of Monitoring Technology for Dysphagia
Recruiting NCT05978700 - Effectiveness of Video-game Based Swallowing Function Training in Patients With Dysphagia N/A
Recruiting NCT06219200 - Automatic Voice Analysis for Dysphagia Screening in Neurological Patients
Enrolling by invitation NCT02935946 - Cold Liquids Fed to Preterm Infants: Efficacy and Safety After 10 Minutes of Exposure N/A
Withdrawn NCT02925507 - Computerized Acoustic Swallowing Evaluation N/A
Completed NCT02379182 - Effect Of Vitalstim In Patients With Chronic Post-stroke Oropharyngeal Dysphagia N/A
Completed NCT02457052 - Impact of a Transportable Customizable and Scalable Sitting Positioning Device on Swallowing Disorders N/A
Completed NCT02825927 - Swallowing Function, Oral Health, and Food Intake in Old Age N/A
Active, not recruiting NCT01559649 - Stroke Swallowing Screening Tool Validation N/A
Completed NCT00439439 - ACHAT-STUDY, Alternative Treatment of Chronic Globus Sensations N/A
Completed NCT00141752 - Toronto Bedside Swallowing Screening Test (TOR-BSST) - A Bedside Swallowing Screening for Stroke Patients N/A
Completed NCT04369092 - Myotonometer Analyses of Muscles in Multiple Sclerosis Patients With Dysphagia N/A
Recruiting NCT06465355 - Effects of an Air Bolus on Primary Peristalsis N/A
Terminated NCT02576470 - Motor Learning in Dysphagia Rehabilitation N/A