Deceased Kidney Transplantation Clinical Trial
Official title:
Oxidative Stress and Postoperatory Renal Function in Deceased Kidney Transplantation
| NCT number | NCT00851708 |
| Other study ID # | NAC vs DKT |
| Secondary ID | FAPESP 06/52046- |
| Status | Completed |
| Phase | N/A |
| First received | February 25, 2009 |
| Last updated | February 27, 2009 |
| Verified date | February 2009 |
| Source | University of Sao Paulo |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | Brazil: Ministry of Health |
| Study type | Interventional |
The aim of this interventional, prospective, randomized clinical trial is to evaluate the impact of the antioxidant N-acetylcysteine on oxidative stress in the first seven postoperative days and on renal function in the first three postoperative months in deceased kidney transplantation.
| Status | Completed |
| Enrollment | 0 |
| Est. completion date | |
| Est. primary completion date | |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - First transplant - Deceased kidney transplant Exclusion Criteria: - postoperative recovery at critical care unit - illicit drug addiction - psychiatric disorders |
Allocation: Randomized, Intervention Model: Parallel Assignment, Primary Purpose: Prevention
| Country | Name | City | State |
|---|---|---|---|
| Brazil | Clinics Hospital, University of Sao Paulo, Medical School | São Paulo |
| Lead Sponsor | Collaborator |
|---|---|
| University of Sao Paulo | Fundação de Amparo à Pesquisa do Estado de São Paulo |
Brazil,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Tiobarbituric acid reactive species measures | First seven postoperative days | No | |
| Secondary | Serum creatinine | 7, 15, 30, 60, 90 postoperative day | No |