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Cytokine clinical trials

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NCT ID: NCT05976516 Recruiting - Cytokine Clinical Trials

CXCL2/CXCL8 Promote Intervertebral Disc Degeneration

Start date: August 1, 2023
Phase:
Study type: Observational

Low back pain (LBP) is the largest cause of morbidity in the world, and about 80% of Chinese people are affected in their lifetime. Although the prevalence of IDD gradually increases with age, IDD is very common among subjects under 30 years old. In addition to age, there are other factors, such as excessive or uneven mechanical load, obesity, genetics, nutrition, trauma and gender. In addition, it is not clear whether the heavy physical load associated with occupation is an important risk factor for IDD. Some studies have found that IDD is more common among athletes than the general population. Due to the complexity and multifactorial nature of IDD, its pathogenesis and risk factors are still unclear, which seriously hinders the rational stratification of LBP patients and limits the development of personalized treatment.

NCT ID: NCT03825471 Recruiting - Opioid Use Clinical Trials

Cranial Electrotherapy Stimulation on Anesthetics Consumption and Postoperative Pain

Start date: January 14, 2019
Phase: N/A
Study type: Interventional

Cranial electrotherapy stimulation (CES) is a non-invasive intervention to treat anxiety, depression, insomnia, and pain. But clinical studies and applications of CES in relation to acute postoperative pain are few. tThe investigators investigate a double-blind, randomized controlled trial to figure out if intraoperative CES could decrease dosage of intraoperative anesthetics and patient-controlled analgesia (PCA) consumption in patients undergoing colon cancer surgery.