Cystocele Clinical Trial
Official title:
Prevalence of Detrusor Underactivity and Bladder Outlet Obstruction in Women With Cystocele and Changes of Voiding Function After Cystocele
Women with cystocele may be associated with detrusor underactivity (DU) or bladder outlet obstruction (BOO). However, the impact of cystocele repair on the rates of DU and BOO remained obscure. Thus, the aim of this study was to elucidate the prevalence of DU and BOO in each age group and elucidate the impact of cystocele repair on the rates of DU and BOO.
Between November 2010 and September 2018, all women with ≥ POP-Q stage II cystocele who
visited the urogynecological department of a medical center for urodynamic evaluation were
reviewed. Those women who have no complete data of maximum flow rate (Qmax), voided volume,
post-void residual volume (PVR) and detrusor pressure at a maximum flow rate (PdetQmax) were
excluded from this study. The DU was defined when the PdetQmax was less than 20 cmH2O, the
Qmax was less than 15 mL/s, and the bladder voiding efficiency (BVE) was less than 90 %. The
BOO was defined when the PdetQmax was not less than 40 cmH2O, and the Qmax was less than 12
mL/s. BVE = voided volume / (voided volume+ PVR) x 100%. Those women without DU or BOO were
allocated to the non-DU/BOO group.
STATA software was used for statistical analysis. Wilcoxon signed-rank test or McNemar's test
was used for statistical analysis as appropriate. P < 0.05 was considered statistically
significant.
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