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Cysticercosis clinical trials

View clinical trials related to Cysticercosis.

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NCT ID: NCT00526916 Completed - Healthy Clinical Trials

PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Neurocysticercosis Using [C-11]PBR28

Start date: September 4, 2007
Phase: Phase 1
Study type: Interventional

The purpose of this protocol is to measure peripheral benzodiazepine receptors in the brain using positron emission tomography (PET) and compare the imaging results between patients and healthy people.

NCT ID: NCT00441285 Completed - Epilepsy Clinical Trials

Neurocysticercosis: Combined Treatment With Praziquantel (PZQ) and Albendazole (ABZ)

Start date: January 2010
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine if combination drug therapy of praziquantel and albendazole is safe and effective to cure neurocysticercosis.

NCT ID: NCT00290823 Completed - Neurocysticercosis Clinical Trials

Corticosteroids to Reduce Frequency of Seizures in Neurocysticercosis Patients

Start date: April 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether a short course of increased corticosteroid dosing with tapered dosing decreases seizure frequency as compared to standard corticosteroid dosing in patients with neurocysticercosis (NCC).

NCT ID: NCT00283699 Completed - Neurocysticercosis Clinical Trials

A Pilot Study of Neurocysticercosis Treatment

Start date: February 2001
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if treatment with albendazole improves the clinical outcome of neurocysticercosis infection and/or leads to the disappearance of cysts sooner when compared with symptomatic treatment.

NCT ID: NCT00004403 Completed - Epilepsy Clinical Trials

Randomized Study of Albendazole in Patients With Epilepsy Due to Neurocysticercosis

Start date: May 2000
Phase: N/A
Study type: Interventional

OBJECTIVES: I. Determine the effect of antiparasitic treatment with albendazole on the severity and duration of epilepsy due to neurocysticercosis. II. Determine the effect of a short course of albendazole on Taenia solium cysts present in the brain. III. Determine the natural regression of cerebral T. solium cysts in patients given placebo and their response to treatment at the end of the study.

NCT ID: NCT00001912 Completed - Seizures Clinical Trials

Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis

Start date: August 10, 1999
Phase: N/A
Study type: Observational

This study will examine what causes seizures in patients with cysticercosis (pork tapeworm infection). A better understanding of this could lead to improved methods of controlling or preventing seizures. In humans, the pork tapeworm (Taenia solium) lives in the small intestine. The parasite's microscopic eggs travel around the body-including to the brain-where they develop into cysts. Usually, the cysts don't cause symptoms until they die. Then, they provoke an inflammatory reaction that irritates the brain, causing seizures and other symptoms. The inflammation eventually goes away, but the dead cysts remain. Calcium deposits often form where the cysts are. Some of the calcified cysts develop swelling around them that seem to be associated with the development of seizures. This study will explore how and why these dead, calcified cysts continue to cause seizures. In so doing, it will try to determine: 1) the best diagnostic imaging method for detecting swelling around the cysts; 2) how often swelling occurs; and 3) what makes some cysts prone to swelling and related seizure activity, while others are not. Patients with cysticercosis who have had seizures or who have known or possible swelling around calcified cysts will be studied with various tests, including magnetic resonance imaging (MRI), computed tomography (CT) scans, electroencephalography (EEG), blood tests, and possibly lumbar puncture. Patients will be studied for two cycles of seizures (during active and quiet periods) or a maximum 4 years.