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Antibiotic Treatment Of Staphylococcus Aureus In Stable People With CF — ASAP-CF  

Cystic Fibrosis Clinical Trial

Official title:
Antibiotic Treatment Of Staphylococcus Aureus In Stable People With CF (ASAP-CF) Clinical Research Protocol

Clinical Trial Summary

This is a randomized, double-blinded study that aims to assess the effect of an oral antibiotic called Cephalexin (150 mg/kg/day) compared to placebo in clinically stable children with cystic fibrosis who have grown a bacteria called MSSA (methicillin-susceptible Staphylococcus aureus) over the course of 2 weeks. A sensitive technique called MBW (multiple breath washout) will be used to look at how well the participants lungs are functioning during the study and to see if the antibiotic improves function. The primary outcome of the study will be the relative change in the MBW measurement (LCI2.5) between day 0 and day 14 of study treatment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04553419
Study type Interventional
Source University of British Columbia
Contact Fareeha Khan
Phone 604-875-2345
Email fareeha.khan@bcchr.ca
Status Recruiting
Phase Phase 3
Start date July 27, 2020
Completion date June 30, 2025
View Details
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