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Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis

Cystic Fibrosis Clinical Trial

Official title:
Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis

Clinical Trial Summary

The study will assess if administration of high-dose vitamin D and a commonly used prebiotic (inulin) is effective to reduce gastrointestinal dysbiosis and to improve critical intestinal functions in Cystic Fibrosis with the additive or synergistic effects of the combination of vitamin D + inulin.

Clinical Trial Description

Cystic fibrosis (CF) is the most common life-shortening genetic condition among Caucasians in the United States. Individuals with CF have an altered gastrointestinal (GI) microbiota, which may be a result of chronic systemic inflammation and infection, frequent use of antibiotics, and/or medically prescribed and habitual high-fat/high-calorie diets. The study will assess if administration of high-dose vitamin D and a commonly used prebiotic (inulin) is effective to reduce gastrointestinal dysbiosis and to improve critical intestinal functions in Cystic Fibrosis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04118010
Study type Interventional
Source Emory University
Contact
Status Completed
Phase Phase 4
Start date March 13, 2020
Completion date December 31, 2022
View Details
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