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Clinical Trial Summary

This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with CF who are ineligible for or unable to tolerate CFTR modulator therapy.


Clinical Trial Description

This Phase 1/2 trial will evaluate the safety, tolerability, and preliminary efficacy of 4 dose levels of 4D-710, an investigational gene therapy, in adults with cystic fibrosis lung disease who are ineligible or unable to tolerate CFTR modulator therapy. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05248230
Study type Interventional
Source 4D Molecular Therapeutics
Contact 4DMT Patient Advocacy
Phone (888) 748-8881
Email clinicaltrials@4DMT.com
Status Recruiting
Phase Phase 1/Phase 2
Start date March 29, 2022
Completion date January 2027

See also
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Recruiting NCT06016088 - A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection Phase 1/Phase 2