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Clinical Trial Summary

Pilot study to investigate the effect of choline chloride in cystic fibrosis patients with liver steatosis by comparing their status before and after the intervention


Clinical Trial Description

Within this single arm pilot study patients with cystic fibrosis and liver steatosis receive choline chloride (2x0.5 gram three times a day) as a food supply for 88 days. D9-choline metabolism is measured before and after the intervention phase. Hypothesis of the study is, that supplying choline augments the secretion of phosphatidyl choline and lipoprotein (VLDL) from the liver and therefore results in a measurable reduction of the triglyceride storage of the liver. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03312140
Study type Interventional
Source University Hospital Tuebingen
Contact
Status Completed
Phase N/A
Start date November 6, 2014
Completion date February 8, 2017

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