Clinical Trials Logo

Clinical Trial Summary

This is a randomized, double-blind, multicenter, phase III study to evaluate the safety and efficacy of 2 dosing regiments of Pasireotide long acting release (LAR) in patients with Cushing's disease.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT01374906
Study type Interventional
Source Novartis
Contact
Status Completed
Phase Phase 3
Start date November 4, 2011
Completion date December 21, 2016

See also
  Status Clinical Trial Phase
Terminated NCT00881283 - Long-term Cardiovascular Risk in Cured Cushing's Patients
Completed NCT02568982 - Cushing's Disease Complications
Completed NCT02697734 - Efficacy and Safety Evaluation of Osilodrostat in Cushing's Disease Phase 3
Recruiting NCT03364803 - Collecting Information About Treatment Results for Patients With Cushing's Syndrome
Not yet recruiting NCT02603653 - Assessment of Persistent Cognitive Impairment After Cure of Cushing's Disease N/A
Completed NCT01371565 - Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome Phase 3
Recruiting NCT00845351 - Preoperative Bexarotene Treatment for Cushing's Disease Phase 1/Phase 2
Completed NCT00889525 - Study of Cabergoline in Treatment of Corticotroph Pituitary Tumor Phase 3
Completed NCT02060383 - Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly Phase 4
Recruiting NCT03474601 - Seoul National University Pituitary Disease Cohort Study
Recruiting NCT04339751 - Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing s Disease Phase 2
Not yet recruiting NCT04569591 - Corticotrophin-releasing Hormone (CRH) Stimulation for 18F-FDG-PET Detection of Pituitary Adenoma in Cushing s Disease N/A
Recruiting NCT02484755 - Targeted Therapy With Gefitinib in Patients With USP8-mutated Cushing's Disease Phase 2
Active, not recruiting NCT01794793 - Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies Phase 4
Completed NCT00434148 - Safety and Efficacy of Different Dose Levels of Pasireotide in Patients With de Novo, Persistent or Recurrent Cushing's Disease Phase 3
Completed NCT03346954 - Impact of [11C]-Methionine PET/MRI in the Detection of Pituitary Adenomas Secreting ACTH and Causing Cushing's Disease N/A
Withdrawn NCT01925092 - Mifepristone in Children With Refractory Cushing's Disease Phase 3
Completed NCT01582061 - An Open-label, Multi-center, Expanded Access Study of Pasireotide s.c. in Patients With Cushing's Disease. Phase 3
Recruiting NCT03708900 - Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Disease Phase 2
Terminated NCT00612066 - Rosiglitazone in Treating Patients With Newly Diagnosed ACTH-Secreting Pituitary Tumor (Cushing Disease) Phase 2