Complex Regional Pain Syndrome Type I of the Upper Limb Clinical Trial
Official title:
Single-port Thoracoscopic Sympathicotomy for Treatment of Complex Regional Pain Syndrome Type I, a Feasibility Study.
Background of the study: CRPS type-1 is a pain syndrome that usually develops after an
initiating noxious event (e.g. fracture) in an extremity. Although treatment options life
dimethyl-sulphoxide (DMSO), N-acetylcysteine (NAC) and intensive physical therapy exist, the
treatment effect is often unsatisfactory, even leading to amputation of the extremity.
Surgical treatment of chronic pain disorders by dividing the sympathetic chain is an
established treatment. Its more invasive nature has prevented widespread application. After
introduction of minimal invasive techniques in recent years, the UMCG has now devised a
truly minimal invasive, yet safe and effective thoracoscopic technique, that requires only a
single 1 cm long incision in the anterior axillary line. This technique is developed as
treatment for primary focal axillary and palmar hyperhidrosis, and is performed in over 50
patients producing very satisfying results. This fact has led to the hypothesis that this
same surgical technique can offer this group of chronic pain patients a safe, effective
treatment modality.
Objective of the study: The effect of the intervention on pain an regain of function in de
affected extremity. This will be quantified in multiple questionnaires at baseline and three
follow-up points, and by clinical evaluation of the hand function at baseline and two
follow-up points.
Study design: Single center prospective feasibility study
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01623141 -
Correlation Between 3 Phase Bone Scintigraphy and Pressure Pain Thresholds in Patients With Complex Regional Pain Syndrome (CRPS)
|
N/A | |
| Recruiting |
NCT05160038 -
Embodied Virtual Reality for Chronic Pain
|
N/A | |
| Recruiting |
NCT01915329 -
Effects of Repetitive Electric Sensory Stimulation (RSS) as Intervention in Complex-regional-pain-syndrome Type I (CRPS)
|
N/A |