Vitamin D Treatment for Crohn´s Disease

Crohns Disease Clinical Trial

Official title: Remission Keeping and Remission Inducing Effect by Vitamin-D in Crohns Disease, and in Vitro Vitamin-D Mediated T-Cell Immunomodulation

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to examine whether vitamin D treatment is effective in Crohn's disease.

Clinical Trial Description

Crohns Disease is an inflammatory disease of primarily the small intestine and colon.

In recent years scientists have hypothesized that low blood vitamin-D levels play a role in the development of autoimmune diseases, including Crohns disease. The purpose of this study is to examine whether vitamin-D is effective in keeping remission in inactive Crohns Disease (double blind placebo controlled trial). The patients who have active disease in the placebo group (reach primary endpoint), will in an open setting receive a higher single dose vitamin-D and the effect will be measured within 4 weeks. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Crohn Disease
• Crohns Disease

• NCT number: NCT00132184
• Study type: Interventional
• Source: University of Aarhus
• Status: Active, not recruiting
• Phase: Phase 2/Phase 3
• Start date: September 2005
• Completion date: February 2008