Crohn Disease Clinical Trial
Official title:
Contribution of a Non Medicamentous Approach by Hypnosis on Quality of Life in Crohn Disease
Evaluation of hypnosis therapy efficacy in addition to pharmacologic standard treatment of Croh disease during remission by the evaluation of quality of life;
Crohn disease is defined as an inflammatory chronic disease of the bowel characterize by
intermittent flare-ups and remission periods.
Crohn disease is due to genetic and environmental factors such as stress. Stress is an
important aggravation factor of the disease symptoms which can stop a remission period and
induce a relapse into a flare-up period.
Hypnosis is a non-medicinal technic which already show efficacy in the treatment of
functional digestive troubles. These diseases are bio/psycho/social models such as Crohn
disease.
Hypnosis can reduce visceral pain sensibility, reduce stress and reduce pro-inflammatory
cytokines liberation into intestinal mucosa.
Though, only few data are available on hypnosis interest in the treatment of Crohn disease
and inflammatory bowel diseases as it is often isolated clinical case report.
One study on patients with rectocolitis in remission period has been done recently and show
that hypnosis increased the duration of the remission period.
The principal objective of this study is to evaluate hypnosis efficacy in term of quality of
life for patients with Crohn disease during remission.
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