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VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit — AKIVEX  

Critical Illness Clinical Trial

Official title:
VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit

Clinical Trial Summary

A quasi experimental study that aims to verify whether the incorporation of VExUS in patients with AKI in the Intensive Care Unit (ICU) may prompt tailored interventions to increases the number of days free from Renal Replacement Therapy (RRT) during the first 28 days.

Clinical Trial Description

Fluid overload is associated with organ dysfunction, such as Acute Kidney Injury (AKI), and increased mortality. It remains unclear if fluid overload is merely an epiphenomenon in critically ill patients or if organ congestion is a mediator of complications. Considering AKI related to fluid overload, diuretic therapy would reduce venous congestion and improve renal blood flow. The Venous Excess Ultrasound score (VExUS) identifies clinically significant venous congestion and indicates a high risk of post-operative AKI. This quasi-experimental study aims to verify whether the incorporation of VExUS in patients with AKI in the Intensive Care Unit (ICU) may prompt tailored interventions to increases the number of days free from Renal Replacement Therapy (RRT) during the first 28 days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05240833
Study type Interventional
Source Hospital de Clinicas de Porto Alegre
Contact MARCIO M BONIATTI, PhD
Phone +55 (51) 3359.8000
Email mboniatti@hcpa.edu.br
Status Recruiting
Phase N/A
Start date January 7, 2022
Completion date December 31, 2022
View Details
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