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Fluid Balance and Body Weight Changes in Critically Ill Adult Patients

Critical Illness Clinical Trial

Official title:
Fluid Balance and Body Weight Changes in Critically Ill Adult Patients

Clinical Trial Summary

Positive fluid status has been consistently associated with worse prognosis in critically ill adult patients.However, observational studies showed poor agreement between fluid balance and body weight changes. The objective of the study is to compare the measurements of FB and BW over time and to assess correlation with ICU mortality.

Clinical Trial Description

Positive fluid status has been consistently associated with worse prognosis in critically ill adult patients. Daily and cumulative fluid balance (FB) is a routine nursing activity in intensive care unit (ICU). In view of the potential for errors in the calculation of FB totals and the problem of accounting for insensible fluid losses, measurement of body weight (BW) changes is an alternative non-invasive method commonly used for estimating body fluid status. Its accuracy over FB assumes a one kilogram change in BW equates to a one liter gain or loss in body fluid volume. However, observational studies showed poor agreement between those measurements, particularly among individuals staying more than a week in ICU possibly due to muscle and fat loss as well as bone demineralization. The objective of the study is to compare the measurements of FB and BW over time and to assess correlation with ICU mortality. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04434079
Study type Observational
Source Hospital de Clinicas de Porto Alegre
Contact
Status Completed
Phase
Start date June 1, 2018
Completion date December 1, 2018
View Details
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