Critical Illness Clinical Trial
— PROTARGETOfficial title:
Meeting Protein Targets in Critically Ill Patients: A Retrospective Analysis
Verified date | September 2018 |
Source | Nestlé |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This is a retrospective study of protein and energy intake in enterally fed critically ill adult patients before and after the introduction of a very high protein enteral nutrition formula in a single center medical/surgical ICU.
Status | Completed |
Enrollment | 40 |
Est. completion date | February 16, 2018 |
Est. primary completion date | February 16, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Adult patients = 18 years of age, mechanically ventilated - Received enteral nutrition for a minimum of five days during the first week of ICU admission Exclusion Criteria: - Received parenteral nutrition during first week of ICU admission - Acute renal failure not dialyzed - Hepatic encephalopathy grade 3 or 4 - Intentional underfeeding/trophic feeding - including refeeding syndrome |
Country | Name | City | State |
---|---|---|---|
Canada | Hamilton Health Sciences | Hamilton | Ontario |
Lead Sponsor | Collaborator |
---|---|
Nestlé | Hamilton Health Sciences Corporation |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Daily total protein intake | Daily total protein intake and percent prescribed protein needs met during first week of ICU admission. | Daily up to 7 days of ICU stay | |
Secondary | Daily caloric intake - Total Calories | Total calories aggregate from all sources | Daily up to 7 days of ICU stay | |
Secondary | Daily caloric intake - kcal/kg | Total volume consumed and weight will be used to measure kcal/kg | Daily up to 7 days of ICU stay | |
Secondary | Daily caloric intake from enteral nutrition | Daily caloric intake from enteral nutrition, and medications (i.e. Propofol) | Daily up to 7 days of ICU stay | |
Secondary | Percentage of prescribed calorie needs met | Percentage of prescribed calorie needs met | Daily up to 7 days of ICU stay | |
Secondary | Feeding interruptions | Feeding interruptions; and reason for interruption, if recorded in electronic medical record/nursing flow sheets | Daily up to 7 days of ICU stay | |
Secondary | Use of inotropes/vasopressors (highest daily dose prescribed) | Use of inotropes/vasopressors will be documented as a Yes/No. | Daily up to 7 days of ICU stay | |
Secondary | Feeding tolerance | Feeding tolerance as recorded by clinicians in electronic medical record/nursing flow sheets [gastrointestinal side effects observed and documented: vomiting, elevated Gastric Residual Volumes (>200 mL), aspiration, pneumonia, diarrhea (Bristol stool chart definition and = 3 liquid stools/day)] | Daily up to 7 days of ICU stay |
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