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Comparison of 250 ml Versus 500 ml of Fluid Challenge — KOBIAS  

Critical Care Clinical Trial

Official title:
Comparison of 250 ml Versus 500 ml of Fluid Challenge on Oxygen Consumption in Critical Care Patients: an Open Label Multicentre Prospective Study

Clinical Trial Summary

The objective of fluid challenge is to increase oxygen delivery (DO2) in order to improve/restore tissue oxygen consumption (VO2). However the fluid challenge volume to administer stills in debate, some studies recommend to administer 250 mL. Previous studies suggested that 500 mL of fluid challenge administration may improve cardiac output and oxygen delivery. The relation between the amount of fluid expansion and oxygen delivery and oxygen consumption was not yet been studied in a randomized study in critical care patients. This is the purpose of this study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03874923
Study type Interventional
Source Centre Hospitalier Universitaire, Amiens
Contact
Status Active, not recruiting
Phase N/A
Start date March 1, 2019
Completion date August 2023
View Details
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