Acute Rehabilitation in Patients With COVID-19 Pneumonia

COVID-19 Clinical Trial

Official title:

Acute Rehabilitation in Patients With COVID-19 Pneumonia a Single Center Experience From a Developing Country

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05619666
• Other study ID #: 02/269-1
• Status: Recruiting
• Phase: N/A
• Start date: September 1, 2021
• Est. completion date: January 2023

Study information

• Verified date: November 2022
• Source: Institut za Rehabilitaciju Sokobanjska Beograd
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

COVID-19 can have different clinical manifestations including myalgia, arthralgia, neurological, cardiac, psychological and other manifestations.These patients are at greater risk of developing consequences of prolonged bed rest. Therefore physical medicine and rehabilitation could have an important role in the multidisciplinary treatment of these issues. Early respiratory and neuromuscular rehabilitation is necessary to improve functional physical limitations, performance, muscle strength, endurance as well as cognitive and emotional domains. Some studies proposed that rehabilitation protocols in the inpatient setting include early mobilisation, strength and endurance training with the aim of reducing weakness and dependency. This Study aimed to detect the effects of rehabilitation in patients with Covid-19 who were admitted in temporary Covid hospital in Serbia. Furthermore, to emphasize the importance of functional assessment of the patients, in identifying their problems and selections of priorities in planning the best therapeutic protocol.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: January 2023
• Est. primary completion date: December 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 95 Years

Eligibility

Inclusion Criteria:

• Positive pharyngeal or nasal swab for SARS CoV-2, 3) SP O2> 94% on admission, 4) body temperature under 37.5 5) Clinical stability defined by ability to perform bedside active mobilization without a reduction of oxygen saturation (SpO2) below 92%;

Exclusion Criteria:

• 1) SP o2 < 94% on admission, 2) Moderate and severe heart failure (grade III and IV, NY heart Association), 3) Paresis or plegia as a result of CVI or neurodegenerative disease, 4) Impaired cognitive status.

Related Conditions & MeSH terms

• COVID-19
• Physical Medicine
• Pneumonia
• Rehabilitation

Intervention

Procedure:
• Acute rehabilitation program
Patients included in the study started the rehabilitation program when they were hemodynamic stable, when it was determined that it was safe for patients. Until discharge from the hospital, a re-evaluation of neuromuscular and respiratory function was performed.

Locations

Country	Name	City	State
Serbia	Institute for Rehabilitation	Belgrade
Serbia	Tamara Filipovic	Belgrade

Sponsors (1)

Lead Sponsor	Collaborator
Institut za Rehabilitaciju Sokobanjska Beograd

Country where clinical trial is conducted

Serbia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	functional outcome of activity of daily living	Bartel index (BI)	up to three weeks
Primary	functional outcome of cardiovascular and respiratory system	six minute walk test (6MWT)	up to three weeks
Primary	functional outcome for assesing dyspnea	Borg scale for dyspnea,	up to three weeks
Primary	functional outcome of mobility	"Time Up and Go" test (TUG)	up to three weeks
Primary	functional outcome of lower limbs strength	"Sit To Stand" test (STS)	up to three weeks
Primary	functional outcome of static balance	"One Leg Stance Test" (OLST)	up to three weeks