Covid19 Clinical Trial
Official title:
Clinical Course of Cancer Patients Who Contracted COVID 19 Infection: An Observational Study
It's an obsevational retrospective/prospective study. Analyzing the evolution of COVID 19
infection in cancer patients can provide interesting information in the management of these
patients. For this reason, the purpose of this study is to implement a registry to describe
and monitor cancer patients affected by COVID 19, the factors that are associated with an
unfavorable evolution, to develop a strategy for the risk assessment of these patients and
recommendations. relating to their treatment.
Particular attention will be paid to patients suffering from urological tumors because the
treatment followed by the patients would seem to expose them to a greater risk when they are
infected with coronavirus, furthermore, from the literature it is clear that there may be a
connection between sex hormones and ACE2 levels in the plasma. In fact, the estrons
up-regulate the concentration of ACE2 in the circulation and this could be the reason why
women would seem more protected than men once they contract the coronavirus infection
Primary objectives:
- describe cancer patients with COVID-19 and their clinical course;
- identify predictors of the most severe clinical course;
- identify prognostic factors; Secondary objectives
- Monitor patients with urological tumors with particular attention;
- Dosing parameters of inflammation such as IL-6 and IFNα;
- Measure the ACE2 levels.
Patients with oncological pathology who contracted COVID 19 infection from January 1, 2020
until the WHO declaration of the end of the pandemic will be studied.
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