COVID Clinical Trial
Official title:
Randomized Clinical Trial to Evaluate Efficacy and Safety of Systemic Indirect Endovenous Ozone Therapy (SIEVOT) as Adjuvant Treatment in COVID19 Non-intubated Patients
Systemic medical ozone has proved to help in several viral diseases, chronic obstructive pulmonary disease and chronic inflammation process. The investigators are sure that its application to COVID-19 patients, as an adjuvant therapy, will improve the health status of these individuals.
Due to the extreme world situation caused by COVID19 pandemic, the investigators consider
unethical not to try any treatment option with a justified rationale.
The investigators have explained that medical ozone therapy has a clear scientific basement
thanks to all preclinical and clinical investigation already published. It can be classified
as chemical stressor that produces a modulation in the redox balance and immunity. Moreover,
it is easy and safe to administer with insignificant side effects.
The efficacy in viral diseases has been proved in publications together the modulation of
interleukin 6 and other proinflammatory cytokines that could potentially help in COVID19
patients. The improve of exchange of gases and microcirculation will surely contribute to
enhance this patients' health status.
As explained above, the investigators propose to carry out a randomized control trial to
evaluate the safety and efficacy of systemic ozone (indirect endovenous) in these patients.
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