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Convalescent Plasma in Outpatients With COVID-19 — C3PO  

Covid19 Clinical Trial

Official title:
Clinical-trial of COVID-19 Convalescent Plasma in Outpatients

Clinical Trial Summary

The overarching goal of this project is to confirm or refute the role of passive immunization as a safe and efficacious therapy in preventing the progression from mild to severe/critical COVID-19 illness and to understand the immunologic kinetics of anti-SARS-CoV-2 antibodies after passive immunization.The primary objective is to determine the efficacy and safety of a single dose of convalescent plasma (CP) for preventing the progression from mild to severe COVID-19 illness. The secondary objective is to characterize the immunologic response to CP administration. This study will enroll adults presenting to the emergency department (ED) with mild, symptomatic, laboratory-confirmed COVID-19 illness, who are at high risk for progression to severe/critical illness, but who are clinically stable for outpatient management at randomization.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04355767
Study type Interventional
Source Stanford University
Contact
Status Completed
Phase Phase 3
Start date August 11, 2020
Completion date March 29, 2021
View Details
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