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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT04422574 Completed - Covid 19 Clinical Trials

COVID 19 Serology in Pulmonologists

Pneumoserocov
Start date: May 1, 2020
Phase:
Study type: Observational

Respiratory physicians are highly exposed workers to Covid-19 as they perform spirometry, endoscopy, and manage Covid-19 in first line for most of them. Moreover, none reported to have apply increased levels of protection for performing these acts in the most active period of viral circulation, until the lockdown. Whether they were most frequently immunized against SARS-CoV-2 at the end of the first wave than the general population is of utmost importance individually but also worldwide

NCT ID: NCT04422561 Completed - COVID Clinical Trials

Prophylactic Ivermectin in COVID-19 Contacts

Start date: May 31, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

asymptomatic family close contact of confirmed COVID -19 patient will receive prophylactic ivermectin and will be followed up for 14 days for any symptoms & diagnosis of COVID -19

NCT ID: NCT04422509 Completed - COVID-19 Clinical Trials

Lanadelumab for Treatment of COVID-19 Disease

COVID_LAN
Start date: October 30, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

So far little is very few drugs have demonstrated positive results for treatment of COVID19. Recently the researchers have shown that the use of icatibant in COVID-19 results in a potent decrease in oxygen use. Yet the effect of the three dosages as according to the label dose was insufficient to maintain the clinical improvement in a small group of patients. The researchers argue that with the use of lanadelumab a more lasting effect can be reached due to its longer half life.

NCT ID: NCT04422470 Completed - Clinical trials for Coronavirus Infection and Hematologic Diseases

Registry of Patients With Hematologic Disease and COVID-19 in Russia

CHRONOS19
Start date: June 22, 2020
Phase:
Study type: Observational [Patient Registry]

This is an observational prospective cohort study to evaluate the clinical course and outcomes of COVID-19 and the underlying disease in patients with hematologic disease (malignant or non-malignant).

NCT ID: NCT04422444 Completed - COVID19 Clinical Trials

Post Intensive Care Syndrome in COVID19 Patients

PICS-COVID19
Start date: June 1, 2020
Phase:
Study type: Observational [Patient Registry]

This project is based in the implementation of a combined monitoring system (technological solutions and medical visits) in survivors of the critical illness due to the infectious disease by COVID-19. The main objective of the project is to characterize the Post-Intensive Care Syndrome (PICS) and detect early needs for specific treatment.

NCT ID: NCT04422379 Not yet recruiting - COVID-19 Clinical Trials

COVID-19 and Liver Injury in Patients With or Without Underlying Liver Disease: A Multi-centre Retrospective-prospective Observational Study

Start date: June 7, 2020
Phase:
Study type: Observational

COVID-19 and liver injury in patients with or without underlying liver disease: A multi-centre retrospective-prospective observational study. All patients infected with SARS-CoV-2 and admitted to the COVID-19 ward/ICU of Max Hospital Saket (either in East Wing , Max Super Specialty Hospital, Saket or MAX Smart Super Specialty Hospital, Saket) between 1/4/2020 to 30/6/2020 (retrospective data between 1/4/2020- 30/5/2020 & prospective data from approval till 30/6/2020), will be included

NCT ID: NCT04422340 Recruiting - Clinical trials for COVID-19 Disease, Severe Form

Senior-COVID-Rea Multicentric Survey

SeniorCOVIDRea
Start date: April 1, 2020
Phase:
Study type: Observational

With the spread of COVID-19 epidemic since 2019 in Wuhan, China health plans have to be adapted continuously in response to the emergency. The first publications from the Chinese experience demonstrate an increase in the incidence of COVID-19 infections in patients over 60 years of age, a higher frequency of severe forms of the disease and therefore theoretical indications of orientation towards resuscitative care. However, the first published data from Hubei province suggest a low benefit of resuscitation for patients between 70 and 80 years of age and null in patients over 80 years of age. These data question the individual benefit / risk balance of an orientation towards resuscitation for this category of patients, their quality of life and the concept of unreasonable obstinacy. Among the covariates associated with resuscitation mortality described in the data published to date, cardiovascular comorbidities, certain biological covariates (LDH, creatinine, lymphocytes, neutrophils, TP, D-dimers, etc.), the time between the first symptoms and the entry into resuscitation have been identified. The objective of this multicentric observational study is to determine the clinical and biological covariates predictive of mortality in the population of patients over 60 years of age admitted in intensive care unit, in particular by integrating functional and nutritional data from patients 1 month before COVID-19 infection.

NCT ID: NCT04421664 Terminated - Clinical trials for Corona Virus Infection

Preemptive Therapy for SARS-Coronavirus-2 (COVID-19 PEP Canada)

Start date: March 25, 2020
Phase: Phase 3
Study type: Interventional

Study Objective: To test if early preemptive hydroxychloroquine therapy can prevent disease progression in persons with known symptomatic COVID-19 disease, decreasing hospitalizations and symptom severity.

NCT ID: NCT04421625 Completed - COVID-19 Clinical Trials

Patients and Health Staff of Cancer Centres During the Covid-19 Pandemic

PAPESCO-19
Start date: June 15, 2020
Phase: N/A
Study type: Interventional

The Covid-19 has, in a few weeks, made the world tremble: the number of deaths (mainly elderly and / or co-morbid) continues to increase, the confinement causes the collapsing of the economy and the decline of relationships inter-human. The data are too fragmented and the disease too recent to know its repercussions on the 3 million French people who have or have had cancer. The investigators would like, in 3 populations: * patients in treatment, * or in follow-up and * health personnel, to constitute a large prospective and longitudinal database of data: i / serological: humoral response, test performance, monitoring of serum immunoglobulin levels , reinfection threshold,…; ii / clinical: incidence, severity, mortality and their favorable factors impact of cancer treatment on Covid-19 infection and modification of the quality of oncological care in the context. In parallel, on a more limited sample of establishments, it will be : * appreciate the economic and functional repercussions, * will try to find out about the infection modalities in patients and health personnel and * will appreciate the levels of anxiety and depression to which health staff are subject.

NCT ID: NCT04421612 Completed - Anxiety Clinical Trials

COVID-19 - No Health Without Mental Health

Co-COVID-19
Start date: April 2, 2020
Phase: N/A
Study type: Interventional

The Corona pandemic is affecting the whole world and since March 12.th 2020 there has been strict qurantene and social isolation interventions in Norway. The aim of this intervention is to reduce the negative and fatal effects of the pandemic. The pandemic and the restrictions that follows it is assumed to affect the mental health of the general population. In this research project we want to examine the use and the effects of a digital self-guided psychological intervention with the aim to increase coping and to reduce psychological problems during and after the pandemic. The participants will be randomized to either an intensive group (new module every 3rd day) or to an ordinary group (new module every 5th day).