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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT04455308 Completed - COVID-19 Clinical Trials

COVID-19 and Chilblains

ECCES
Start date: July 21, 2020
Phase: N/A
Study type: Interventional

Chilblains (inflammatory lesion of the feet or hands) have been reported with an unusual frequency during the confinement period, most commonly in children, teenagers and young adults. The aim of the ECCES study is to find out whether these manifestations of chilblains can be linked to the SARS-CoV-2 coronavirus. For this, an epidemiologic study will compare two types of family (or more precisely people who were confined together in March-April-May): - "case family" in which at least one of the members had chilblains - "comparator family" in which none of the members had chilblains Environment (home lockdown) of the two types of family will be analyzed. Each member of the "family" will be suggested doing a serological test.

NCT ID: NCT04455243 Not yet recruiting - COVID-19 Clinical Trials

Inflammatory Regulation Effect of NAC on COVID-19 Treatment

INFECT-19
Start date: August 1, 2020
Phase: Phase 3
Study type: Interventional

Study times to evaluate the efficacy of N-Acetylcysteine therapy in the management of adult admitted patients with COVID-19.

NCT ID: NCT04454606 Completed - COVID Clinical Trials

The New Silicone N99 Half-Piece Respirator

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

Filter facepiece respirator (FFR) is a critical equipment to prevent the transmission of respiratory tract infection disease especially the dreadful corona virus 2(SARs-CoV-2).The N95 mask is the prototype of high efficiency protective device and can effectively protect airborne pathogens of less than 0.3 μm by more than 95%. It is tightly fit and had high filtration capacity. The widespread pandemic of COVID-19 leads to greater requirement of FFR. A rising in demand would greatly exceed current productive capabilities and stockpiles and would almost certainly result in a robust shortage. In order to solve these problems, our team had invented a new type of half-piece respirator made from silicone and assembled with hepa or elastostatic filter . A variety of methods have been used to evaluate this new device, including qualitative fit test with Bitrex® test kit and filtration test.

NCT ID: NCT04454398 Withdrawn - Covid-19 Clinical Trials

Study to Evaluate STI-1499 (COVI-GUARD) in Patients With Moderate COVID-19

Start date: September 2020
Phase: Phase 1
Study type: Interventional

Randomized, placebo-controlled study to evaluate the safety, pharmacokinetics and efficacy of a single dose of STI-1499 (COVI-GUARD™) in hospitalized patients with moderate COVID-19

NCT ID: NCT04454372 Completed - COVID-19 Clinical Trials

Clinical Characteristics and Outcomes of 187 Critically Ill Patients With Coronavirus Disease 2019 (COVID-19)

Start date: July 15, 2020
Phase:
Study type: Observational

This case series describes the clinical characteristics, treatment and outcomes of patients with laboratory confirmed COVID-19 admitted to a 35 beds intensive care unit of a tertiary hospital in Northeast Brazil.

NCT ID: NCT04454333 Completed - Pain Clinical Trials

COVID-19 in Pain Perspective

Start date: June 3, 2020
Phase:
Study type: Observational

In our hospital's Infectious Diseases and Clinical Microbiology service, patients who have been hospitalized due to Covid -19 infection have a musculoskeletal pain and headache during this process, and 466 patients will be recruited to compare them with the pre-disease state of the patients and to evaluate the pain status of the patients after treatment.

NCT ID: NCT04454307 Not yet recruiting - COVID-19 Clinical Trials

Safety and Efficacy of Tramadol in COVID-19 Egyptian Patients

Start date: July 2020
Phase: Phase 1/Phase 2
Study type: Interventional

The rationale of the use of tramadol for COVID-19 patients is attributed to its anti-inflammatory, hypocagulatory, antioxidant, cardio-protective, analgesic, antitussive, bactericidal and antidepressant effect.

NCT ID: NCT04453891 Withdrawn - COVID-19 Clinical Trials

Hexoskin Feasibility Study With COVID-19 Patients

Start date: July 15, 2022
Phase:
Study type: Observational

This pilot study aims to investigate the feasibility of using Hexoskin cardiorespiratory and activity data, as well as patient symptomatology, to provide an AI model for disease progression that will be at the service of the clinical team to recommend the best customized and evolving care trajectory for each patient.

NCT ID: NCT04453852 Completed - COVID Clinical Trials

Monovalent Recombinant COVID19 Vaccine

COVAX19
Start date: June 30, 2020
Phase: Phase 1
Study type: Interventional

This is a study to test a new vaccine (Covax-19) against COVID-19. COVID-19 is a potentially deadly disease that is caused by a new strain of coronavirus called SARS-CoV-2. To date, SARS-CoV-2 has infected over 4 million people worldwide resulted in the deaths of over three hundred thousand people.

NCT ID: NCT04453839 No longer available - Clinical trials for Critical COVID-19 With Respiratory Failure

ZYESAMI (Aviptadil) Intermediate Population Expanded Access Protocol (SAMICARE)

SAMICARE
Start date: n/a
Phase:
Study type: Expanded Access

Patients with Critical COVID-19 and respiratory failure who are ineligible for enrollment in NCT04311697, who live more than 50 miles from an existing collaborating research center, or who are already hospitalized and cannot safely be transferred to a collaborating research facility may be considered for expanded access by the sponsor. Treating physicians must complete FDA Form 3396 and receive a letter of authorization from NeuroRx, along with local IRB authorization. Please refer to FDA guidance for Individual Patient Expanded Access https://www.fda.gov/media/91160/download