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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT04460534 Completed - COVID Clinical Trials

Detection of COVID-19 (SARS-CoV-2) in the Semen of COVID+ Patients (Positive RT-PCR on a Nasopharyngeal Swab)

COVISPERM
Start date: May 7, 2020
Phase: N/A
Study type: Interventional

The objective of this study is to look for the presence of SARS-CoV-2 in the semen of patients diagnosed with COVID+ based on RT-PCR analysis of nasopharyngeal swabs.

NCT ID: NCT04460469 Completed - Anxiety Clinical Trials

Anxiety Level and Oral Hygiene Practice in Dental Students During Covid-19 Pandemic

Start date: July 1, 2020
Phase:
Study type: Observational

Covid-19, the infection caused by a novel corona virus detected in December 2019 in Wuhan (Hubei province), is now a pandemic announced by World Health Organization, raising concerns of widespread panic and increasing anxiety in individuals. This outbreak results in mass quarantine in Egypt since middle of March 2020. Brooks et al. (2019) reviewed and reported quarantine could bring "post traumatic stress symptoms, confusion, and anger. Stressors included longer quarantine duration, infection fears, frustration, boredom, inadequate supplies, inadequate information, financial loss, and stigma.". Many universities decided to suspend in-person classes and evacuate students in responding to the intensifying concerns surrounding Covid-19. This action can lead to negative psychological consequences among college students. Oral health related behavior and attitudes habits correlate with oral health status and can be considered to be its predictors . There is a claim of potential connection between high bacterial load in the mouth and complications associated with Covid-19 infection. Bacteria present in the meta genome of patients severely infected with Covid-19 included high reads for Prevotella, Staphylococcus, and Fusobacterium, all usually commensal organisms of the mouth. Over 80% of patients in ICU exhibited an exceptionally high bacterial load. Accordingly, the investigators assume that good oral hygiene better to be maintained during a Covid-19 outbreak in order to reduce the bacterial load in the mouth and the risk of a bacterial super infection in case of catching the infection . While there seems to be a common belief that psychosocial stress affects oral hygiene behavior, this assumption has rarely been proved9 Dental students, as the future providers of dental care, are ex¬pected to be role models for their patients regarding the oral hygiene practice and they supposed to be aware of the importance of preserving the oral health. Thus, we intended to select them as our population to study how the level of anxiety during pandemic could affect the practice of oral hygien

NCT ID: NCT04460443 Recruiting - COVID Clinical Trials

Sofosbuvir in Treatment of COVID 19

Start date: August 1, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

Sofosbuvir containing treatment in treatment of COVID 19 Egyptian patients

NCT ID: NCT04460274 Completed - Covid-19 Clinical Trials

Forecast Number of Covid-19 Cases Worldwide

Covid19TmeSer
Start date: December 31, 2019
Phase:
Study type: Observational

Coronavirus disease-19 (Covid-19) had an unprecedented effect on both nations and health systems. Time series modeling using Auto-Regressive Integrated Moving Averages (ARIMA) models have been used to forecast variables extensively mainly in statistics and econometrics. The investigators aimed to predict the total number of cases for Covid-19 using ARIMA models of time-series analysis.

NCT ID: NCT04460183 Completed - COVID-19 Clinical Trials

A Study to Assess Efficacy and Safety of RESP301 Plus Standard of Care (SOC) Compared to SOC Alone in Hospitalized Participants With COVID-19

Start date: July 29, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The effect of RESP301 as an add on treatment to SOC will be evaluated for its efficacy in reducing rate of progression to a more severe level of COVID-19 and for safety, by comparison with SOC alone in hospitalized COVID-19 patients.

NCT ID: NCT04460170 Recruiting - COVID-19 Clinical Trials

COVID-19 Follow up Intensive Care Studies

COFICS
Start date: July 1, 2020
Phase:
Study type: Observational [Patient Registry]

Since the SARS-CoV-2 infection is relatively new, the long term attributable burden related to COVID19 has not been investigated yet. To date, in patients with COVID-19 and their family members, there is little information on the functional status, cognitive ability, pattern of return to work, and health related quality of life after the ICU admission. This study aims to describe the psychological wellbeing, physical - and social functioning of COVID-19 ICU survivors and their family members up to 12 months following ICU discharge.

NCT ID: NCT04460105 Withdrawn - COVID-19 Pneumonia Clinical Trials

Lanadelumab in Participants Hospitalized With COVID-19 Pneumonia

Start date: October 31, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, pharmacokinetic and pharmacodynamics of lanadelumab administered by intravenous (IV) infusion when added to standard-of-care (SoC) in adults hospitalized with COVID-19 pneumonia.

NCT ID: NCT04459962 Completed - Covid-19 Infection Clinical Trials

Covid-19 Breath Test

Start date: June 29, 2020
Phase: N/A
Study type: Interventional

Can Nanotechnology Biomarker Tagging (NBT) be used to detect COVID-19 infection in people presenting for COVID-19 testing? NBT can be used to detect the substances present in a person's breath. In this study the breath of people presenting for COVID-19 testing is going to be analysed. Analysing a large number of samples from people with COVID-19 (as confirmed by the standard swab test used by the NHS) will enable a breath profile to be produced, ie the substances present in the breath when someone has COVID-19. After the profile has been validated, NBT can be used to test whether or not a person has COVID-19 by seeing if their breath matches the profile. Using this technology for COVID-19 testing has advantages over the current standard test. The sample can be analysed immediately in the clinical setting and the results are available in 5-10 minutes, so if the person tests negative they can go back to their normal life straight away. The current swab test takes around 72 hours for the results to be available, and the person needs to self-isolate during this time in case they test positive, resulting in potentially unnecessary days of work missed and inconvenience. The breath test is non-invasive and is unlikely to cause any discomfort, as the person is only required to breath normally into the device. This study will also review the practicalities of using this test. It is quick and easy to train people in how to carry out the test, so it could potentially easily be rolled out to testing sites.

NCT ID: NCT04459819 Completed - COVID-19 Clinical Trials

Respiratory Physiotherapy in Severe COVID-19 Patients

FTR-COVID
Start date: March 1, 2020
Phase:
Study type: Observational

COVID-19 is an infectious disease caused by SARS-CoV2 virus. COVID-19 patients can develop a severe disease that can lead to hypoxic respiratory failure and acute respiratory distress syndrome (ARDS). Severe patients can require access to intensive care unit (ICU). Early rehabilitation is known to be effective in critically ill patients and in ARDS. The role of respiratory physiotherapy in critical COVID-19 patients is still unclear. The aim of this study is to describe the bundle and the timing of respiratory physiotherapy used with severe COVID-19 patients from ICU to hospital discharge. Functional condition of patients at discharge will be assessed and described.

NCT ID: NCT04459702 Withdrawn - COVID-19 Clinical Trials

A Study of Combination Therapies to Treat COVID-19 Infection

Start date: July 2020
Phase: Phase 2
Study type: Interventional

This study seeks to determine whether dual or quadruple therapy is more effective in treating COVID-19.