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Covid19 clinical trials

View clinical trials related to Covid19.

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NCT ID: NCT04765540 Completed - Covid19 Clinical Trials

The Effect of Behaviour Change Interventions on Use of Public Handwashing Stations in Bangladesh

Start date: January 3, 2021
Phase: N/A
Study type: Interventional

As part of the COVID-19 response, BRAC has built 1000 public handwashing stations in several hundred villages in 20 sub-districts of Bangladesh. The investigators investigate the effects of two sets of behavioural interventions on use of the handwashing stations, compared to no additional interventions. The first set comprises passive nudges installed on and around the handwashing station, aimed at attracting people to the station. The second set comprises actively delivered higher-intensity interventions, including free soap offered as an incentive for using the handwashing station and a community board used to display social proof. This set of interventions aims to increase motivation to use the station.

NCT ID: NCT04765475 Completed - COVID-19 Clinical Trials

Protecting Native Families From COVID-19

Start date: March 8, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to increase and hasten testing among those with COVID-19 symptoms and improve adherence to recommended strategies following positive test results in high-risk groups in the White Mountain Apache and Navajo Nation communities.

NCT ID: NCT04765449 Completed - Covid19 Clinical Trials

Transfer of Infection Fighting Immune Cells Generated in the Laboratory to High Risk Patients With COVID-19 Infection

Start date: September 15, 2021
Phase: Phase 1
Study type: Interventional

This clinical trial will study the safety and efficacy of COVID-19-specific T cells when given as treatment to adult patients (age ≥ 18 years) with a COVID-19 infection. This immunologic treatment is aimed at patients, who are at high risk of progression due to their advanced age, or other underlying health conditions. The outcomes of patients receiving the T cells (Arm A) will be compared to patients treated with standard of care (Arm B).

NCT ID: NCT04765436 Completed - Covid19 Vaccine Clinical Trials

PTX-COVID19-B, an mRNA Humoral Vaccine, is Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Evaluate Safety, Tolerability, and Immunogenicity of PTX-COVID19-B Vaccine in Healthy Seronegative Adults Aged 18-64

Start date: January 14, 2021
Phase: Phase 1
Study type: Interventional

The Vaccine Product, PTX-COVID19-B mRNA Humoral Vaccine, is intended for prevention of COVID-19 in a general population. This study is designed to evaluate the safety, tolerability, and immunogenicity of PTX-COVID19-B vaccine in healthy seronegative adults aged 18 to 64.

NCT ID: NCT04765384 Completed - COVID-19 Prevention Clinical Trials

A Study of Ad26.COV2.S in Healthy Pregnant Participants (COVID-19)

HORIZON 1
Start date: August 27, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety and reactogenicity of Ad26.COV2.S administered intramuscularly (IM) as a 1-dose schedule at the standard dose level in adult participants during the second and/or third trimester of pregnancy and (potentially) post-partum; to assess the humoral immune response in peripheral blood of adult participants to Ad26.COV2.S administered IM as a 1-dose schedule during the second and/or third trimester of pregnancy, 28 days after vaccination.

NCT ID: NCT04765371 Completed - Clinical trials for Coronavirus Infection

Comparison Between Prednisolone and Dexamethasone on Mortality in Patients on Oxygen Therapy, With CoViD-19

COPreDex
Start date: March 3, 2021
Phase: Phase 3
Study type: Interventional

The aim of the study is to evaluate two differents regimens of corticosteroids (prednisolone versus dexamethasone) on D28 mortality in patients with CoViD 19 pneumonia requiring oxygen supplementation

NCT ID: NCT04765254 Recruiting - Covid19 Clinical Trials

COVID-19 Infection in Diabetic Patients

Start date: February 20, 2021
Phase:
Study type: Observational

It was observed during the last period of COVID-19 pandemic that diabetic patients had a worse prognosis and more deteriorated clinical features than other patients

NCT ID: NCT04764981 Enrolling by invitation - Covid19 Clinical Trials

Olfactory Training for Olfactory Dysfunction After Coronavirus Disease - 19 (COVID-19)

Start date: May 2021
Phase: N/A
Study type: Interventional

It is a randomized controlled clinical trial study that aims to follow a sample of individuals with persistent olfactory dysfunction post-COVID-19. The aim of this study is assess the clinical outcomes of olfactory training therapy in the treatment of persistent olfactory dysfunctions after COVID-19. The sample will consist of 350 participants, being 300 individuals with persistent olfactory dysfunction post-COVID-19 and 50 healthy individuals. Volunteers' will be separated in two experimental groups (1 and 2 ) and a control group. All participants will be submitted to clinical evaluation that include the Connecticut Chemosensory Clinical Research Test (CCCRT), an olfactory test to diagnose anosmia and hyposmia, and two skull Magnetic Resonance imaging (MRI). Only participants of Experimental group 1 will be submitted to an olfactory training with essences oils. Experimental group 2 will only receive a clinical follow-up after three months and control group will be only submitted to neurological exam, olfactory test, MRI imaging and test their ability to discriminate the essence oils used in olfactory training. As a result, is expected a better understanding of the characteristics of olfactory dysfunction caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) virus infection, as well as the effectiveness and viability of using Olfactory Training as a therapeutic alternative.

NCT ID: NCT04764773 Completed - Clinical trials for Corona Virus Infection

Persistence of Symptoms After Improvement of Acute COVID-19

COVID-19
Start date: May 1, 2020
Phase:
Study type: Observational

Coronavirus disease pandemic has been started in late 2019. Survivors of COVID-19 are significantly more likely to develop clinical sequelae three months after discharge from the hospital than those without COVID-19 infection. This is true not only for general and respiratory symptoms but also for cardiovascular and psychosocial symptoms. This suggests that these symptoms may indeed be the sequelae of recovery for COVID-19 survivors. So, we aimed to detect the prevalence and to evaluate the type of symptoms that could persist after the recovery from COVID19 infection in Sohag governorate, Egypt.

NCT ID: NCT04764747 Completed - Covid19 Clinical Trials

Effectiveness of Convalescent Plasma in Hospitalized Patients With COVID-19

Start date: November 1, 2020
Phase:
Study type: Observational

Multicenter retrospective cohort study from June to August 2020 on hospitalized COVID-19 patients admitted to Al-Hakeem and Al-Amal hospital in Al-Najaf Governorate, Iraq, in order to evaluating the effectiveness of plasma therapy in hospitalized patients with COVID-19 and analyzing factors that affect therapeutic outcome, either related to patients or related to donors.