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Covid19 clinical trials

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NCT ID: NCT04996212 Completed - Clinical trials for Coronavirus Infection

Telerehabilitation Program in Persistent COVID-19

COVIDPERS
Start date: January 20, 2021
Phase: N/A
Study type: Interventional

The syndrome characterized by the persistence of symptoms typical of COVID-19, beyond 4 weeks after discharge, is called long COVID. Long COVID affects a high percentage of patients who have suffered from COVID-19, regardless of its severity. The various symptoms present in that patients affect the functionality and physical, mental and psychological capacities of patients. Therefore, it is necessary to implement therapeutic programs, based on exercises and techniques of physiotherapy, to help affected people to resume their work, family, social and sports activities; prior to illness. Given the context in which these programs must be developed, telecare is positioned as the most recommended care method to carry out the rehabilitation of these patients. The general objective of this study is to evaluate the effectiveness of a cardiorespiratory tele-rehabilitation program in persistent COVID-19 patients. Study participants (n=60) will be randomly assigned to one of two intervention groups. Group 1 will combine breathing exercises with aerobic exercise: walk; and group 2 will perform functional exercises in addition to respiratory physiotherapy with. All participants will be evaluated at the beginning of the intervention, at the end of it.

NCT ID: NCT04993586 Completed - Clinical trials for COVID-19 Lower Respiratory Infection

Phase I/II Study of COVID-19 DNA Vaccine (AG0302-COVID19 High-dose)

Start date: July 29, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

This study will assess the safety and immunogenicity of AG0302-COVID19 in healthy volunteers.

NCT ID: NCT04993560 Completed - Covid19 Clinical Trials

Safety and Efficacy of COVID-19 Prime-boost Vaccine in Bahrain

Start date: July 18, 2021
Phase:
Study type: Observational

Coronavirus disease 2019 (COVID-19) is potentially a deadly disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that targets the lung mainly, resulting in respiratory tract infections in humans. It has developed into a pandemic with serious global public health problems. Recent research has shown that the new SARS-CoV-2 variants reduces the efficacy of the vaccinations and are predominantly more transmissible or infective. A few countries namely Bahrain, United Arab Emirates, and Turkey have recently started introducing a booster dose following primary two doses of the COVID-19 immunization series. This study aims to identify which booster dose is more effective; taking a booster dose from the same vaccine initially taken or a booster dose from a different vaccine than initially taken.

NCT ID: NCT04993365 Completed - COVID-19 Clinical Trials

Immunogenicity And Safety of COVID-19 Vaccine , Inactivated Co -Administration With EV71 Vaccine (Vero Cell)

Start date: November 5, 2021
Phase: Phase 4
Study type: Interventional

This study is a randomized and controlled phase Ⅳ clinical trial of the COVID-19 vaccine (Vero cell), Inactivated manufactured by Sinovac Research & Development Co., Ltd. The purpose of this study is to evaluate the immunogenicity and safety of COVID-19 vaccine (Vero cell), Inactivated co-administration with EV71 vaccine

NCT ID: NCT04993209 Completed - Healthy Clinical Trials

Clinical Trial of the COVID-19 Vaccine (Recombinant, Inactivated) in Brazil

ADAPTCOV
Start date: July 9, 2021
Phase: Phase 1
Study type: Interventional

NDV-HXP-S is an inactivated COVID-19 vectored-vaccine virus using the Newcastle Disease Virus as basis and expressing S protein from SARS-CoV-2 stabilized in pre-fusion form with Hexapro technology. This vaccine was successfully tested in non-clinical study with a good safety profile and eliciting neutralizing antibodies against SARS-CoV-2. Clinical testing is conducted by an international consortium including three different manufacturers. Butantan, in Brazil, is one of them.

NCT ID: NCT04992260 Completed - COVID-19 Clinical Trials

Efficacy, Immunogenicity and Safety of COVID-19 Vaccine , Inactivated in Children and Adolescents

Start date: September 10, 2021
Phase: Phase 3
Study type: Interventional

This study is a global multi-center , case-driven, randomized, double-blinded, and placebo-controlled phase Ⅲ clinical trial of the SARS-CoV-2 inactivated vaccine manufactured by Sinovac Research & Development Co., Ltd. The purpose of this study is to evaluate the efficacy of two dose of CoronaVac® against RT-PCR confirmed symptomatic COVID-19 cases in participants aged 6 months to 17 years.

NCT ID: NCT04992208 Completed - COVID-19 Clinical Trials

Safety of an Inactivated SARS-CoV-2 Vaccine for Prevention of COVID-19 in Children and Adolescents

Start date: July 24, 2021
Phase: Phase 4
Study type: Interventional

This study is a multi-center and open design, phase Ⅳ clinical trial of an inactivated SARS-CoV-2 vaccine (CoronaVac) manufactured by Sinovac Research and Development Co., Ltd.The purpose of this study is to evaluate the safety of the SARS-CoV-2 Inactivated vaccine in population aged 3~17 years and in people with pre-existing disease to provide reference for improving the immunization strategy of COVID-19 vaccine.

NCT ID: NCT04991246 Completed - Covid19 Clinical Trials

Project FLUx COntact-CoVID-19 Faculty of Medicine Paris-Saclay

FLUCOVID
Start date: October 14, 2021
Phase: N/A
Study type: Interventional

The worldwide health system has been marked by the SARS-CoV-2 pandemic. French educational system has been upset, especially medical schools, which, because of their hospital location, are particularly exposed to the spread of the virus. The medical school of Paris-Saclay University, located within bicetre University Hospital, AP-HP, must therefore adapt on a daily basis to ensure educational continuity. Taking advantage of an exceptional scientific ecosystem, innovative viral epidemic propagation modeling approaches based on both simulation and contact tracing data will be tested in real-life conditions. These propagation models will serve to scientifically optimize future educational organization procedures in this medical school.

NCT ID: NCT04990570 Completed - Covid19 Clinical Trials

Telemedicine (Virtual Clinic) for Pediatric Surgery During Covid-19 Pandemic

TelemedCov
Start date: June 1, 2019
Phase:
Study type: Observational [Patient Registry]

Telemedicine (Virtual Clinic) Effectively Delivers the Required Health-care Service to Pediatric Day-case Surgical Patients in the Current Era of Covid-19 Pandemic: A Non-randomized Controlled Study

NCT ID: NCT04990505 Completed - Clinical trials for SARS-CoV-2 Infection

Microvascular Injury and Distal Thrombosis in COVID-19

MIND
Start date: February 22, 2020
Phase:
Study type: Observational

Investigators aimed to better understand the pathophysiology of SARS-CoV-2 pneumonia in non-critically ill hospitalized patients secondarily presenting with clinical deterioration and increase in oxygen requirement