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NCT ID: NCT03986476 Completed - IBS Clinical Trials

The Effect of Two Probiotic Products on the Intestinal Barrier Function in Patients With Irritable Bowel Syndrome

Start date: March 26, 2019
Phase: N/A
Study type: Interventional

This study will investigate the effects of supplementation with two different probiotic products (Lactobacillus reuteri strains) on the intestinal barrier function, gut health and stress symptoms in diarrhoea-predominant irritable bowel syndrome (IBS-D) patients.

NCT ID: NCT03985514 Completed - Appendicitis Clinical Trials

Acute Appendicitis: Active Observation With and Without Antibiotics

Start date: May 15, 2018
Phase: Phase 4
Study type: Interventional

This study evaluates if early provision of antibiotics is a superior treatment compared to "traditional wait and see" with regard to symptom relief for suspected acute uncomplicated appendicitis.

NCT ID: NCT03983031 Completed - Clinical trials for Obsessive-Compulsive Disorder

Rituximab for Obsessive-compulsive Disorder. (RITS-PO-2019)

Start date: August 8, 2019
Phase: Phase 1
Study type: Interventional

This study evaluates the addition of rituximab to 12 patients diagnosed with treatment resistant obsessive-compulsive disorder in an open trial.

NCT ID: NCT03983018 Completed - Clinical trials for Schizophrenia Spectrum and Other Psychotic Disorders

Rituximab for Schizophrenia Spectrum Disorder (RITS-PS-2019)

Start date: August 7, 2019
Phase: Phase 1
Study type: Interventional

This study evaluates the addition of rituximab to 12 patients diagnosed with treatment resistant schizophrenia spectrum disorder in an open trial.

NCT ID: NCT03979313 Completed - Clinical trials for Respiratory Syncytial Virus Infections

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY)

MELODY
Start date: July 23, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics (PK), and antidrug antibody (ADA) response for MEDI8897 in healthy late preterm and term infants who are 35 weeks or greater gestational age and entering their first RSV season.

NCT ID: NCT03974321 Completed - Myocardial Injury Clinical Trials

Intraoperative Hypotension and Perioperative Myocardial Injury

Start date: May 1, 2019
Phase:
Study type: Observational [Patient Registry]

Acute myocardial infarction (MI) is a significant complication following non-cardiac surgery. We sought to evaluate incidence of perioperative MI, its preoperative - and intraoperative - risk factors and outcomes after this complication.

NCT ID: NCT03974126 Completed - Clinical trials for Postprandial Glucose and Insulin Response

Postprandial Effect of High-starch Meals in Individuals With Low and High Copy Number of the Salivary Amylase Gene

Start date: April 30, 2019
Phase: N/A
Study type: Interventional

Individuals with low copy numbers of salivary amylase gene have lower salivary amylase levels and might therefore have decreased capacity to metabolize starch into glucose. We will in a randomized crossover meal study examine the postprandial response of high-starch meals in individuals with either low or high copy number of the salivary amylase gene.

NCT ID: NCT03973814 Completed - Acute Kidney Injury Clinical Trials

Hypothermia Risk With Continuous Renal Replacement Therapy

HR-CRRT
Start date: August 1, 2022
Phase: N/A
Study type: Interventional

The present study aims at testing if the TherMax blood warmer is more accurate and reliable in reaching and maintaining chosen target temperature during continuous renal replacement therapy as compared to the Prismaflo IIS blood warmer used for the PrismaFlex system.

NCT ID: NCT03972475 Completed - Critical Care Clinical Trials

The Effect of Maintenance Fluids on Overall Fluid Balance in ICU Patients

Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

The amount of fluids characterized as non-resuscitation fluids given to ICU patients are likely to be high and will probably have a substantial impact on the total amount of fluid administered to ICU patients daily. It will most likely also influence on the total fluid balance and the negative outcome of fluid overload. The aim of our study is to investigate the amount of fluid given as maintenance fluids in the ICU and the impact of this fluid on total fluid balance.

NCT ID: NCT03970356 Completed - Clinical trials for Urinary Tract Infections

Improving Antibiotic Prescribing for Urinary Tract Infections in Frail Elderly

ImpresU-WP2
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a tailored multifaceted antibiotic stewardship intervention reduces antibiotic use for urinary tract infections in residential care homes and nursing homes attended by general practitioners. This will be evaluated in a pragmatic cluster randomised controlled trial using a modified community-based participatory action research approach.