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NCT ID: NCT02584764 Completed - Hoarding Disorder Clinical Trials

Internet Supported Group Cognitive Behavior Therapy (CBT) for Hoarding Disorder (HD)

Start date: October 2015
Phase: N/A
Study type: Interventional

The primary aim is to develop, and test the feasibility and efficacy of, a manual based, cognitive behaviour therapy (CBT) treatment for Hoarding Disorder (HD) delivered in a group format combined with an Internet support system. The investigators' secondary aim is to investigate the neurocognitive profile of the participants before and after treatment in order to explore if the treatment might have an impact on neurocognitive functioning and if certain neurocognitive profiles predict outcome. For the primary aim, the investigators hypothesize that the treatment will be acceptable to participants and decrease symptoms of hoarding. Regarding the secondary aim, the investigators hypothesize that deficiencies in executive functioning, as measured with a neurocognitive battery, will reduce upon completion of treatment and that baseline executive function will be associated with treatment outcome.

NCT ID: NCT02582866 Completed - Epilepsy Clinical Trials

A Clinical Study to Investigate the Long-term Use of Lacosamide as Monotherapy in Subjects Who Completed Study SP0994

Start date: January 2016
Phase: Phase 3
Study type: Interventional

Study is conducted to evaluate the long-term safety and tolerability of lacosamide (LCM) in patients receiving LCM in SP0994 [NCT01465997]. The study will enable collection of additional monotherapy safety data, and will facilitate access to treatment until commercial availability for monotherapy use.

NCT ID: NCT02581878 Completed - Clinical trials for Lymphoma, Non-Hodgkin

Safety and Tolerability of BAY1862864 Injection in Subjects With Relapsed or Refractory CD22-positive Non-Hodgkin's Lymphoma

Start date: November 20, 2015
Phase: Phase 1
Study type: Interventional

To establish a recommended dose of BAY1862864 Injection and to investigate how the study drug acts in the body, on the cancer cells and how safe it is in patients with advanced non-Hodgkin's lymphoma (NHL)

NCT ID: NCT02581644 Completed - Renal Transplant Clinical Trials

Assessment of Effectiveness of Belatacept Patient Alert Card in Patients Following Renal Transplantation in a Sample of EU Countries

Start date: November 29, 2016
Phase: N/A
Study type: Observational

The purpose of the study is to determine a) if the implementation of belatacept patient alert card (PAC) resulted in effective understanding of key safety messages and b) if the degree of understanding of key safety messages is associated with improved clinical and safety outcomes.

NCT ID: NCT02580591 Completed - Clinical trials for Diabetes Mellitus, Type 1

Empagliflozin as Adjunctive to Insulin Therapy Over 26 Weeks in Patients With T1DM (EASE-3)

Start date: December 22, 2015
Phase: Phase 3
Study type: Interventional

The study will investigate the efficacy, safety, tolerability and Pharmacokinetic(PK) of 3 doses of empagliflozin compared with placebo over 26 weeks in 960 patients with type 1 diabetes mellitus as adjunctive therapy to insulin

NCT ID: NCT02580110 Completed - Healthy Subjects Clinical Trials

On the Impact of Common Sweetening Agents on Glucose Regulation, Cognitive Functioning and Gut Microbiota

Start date: October 2015
Phase: N/A
Study type: Interventional

The study intention is to investigate, in healthy humans, effects of 3 commonly used sweeteners on cardiometabolic risk markers, cognitive functions, and influences on gut microbiota composition.

NCT ID: NCT02579252 Completed - Alzheimer's Disease Clinical Trials

24 Months Safety and Efficacy Study of AADvac1 in Patients With Mild Alzheimer's Disease

ADAMANT
Start date: March 2016
Phase: Phase 2
Study type: Interventional

This study evaluates the safety and efficacy of AADvac1 in the treatment of patients with mild Alzheimer's disease. 60% of participants will receive AADvac1 and 40% of participants will receive placebo.

NCT ID: NCT02576860 Completed - Rosacea Clinical Trials

Study to Evaluate the Safety and Efficacy of a Once-Daily CLS001 Topical Gel Versus Vehicle

Start date: October 2015
Phase: Phase 3
Study type: Interventional

This study evaluates the safety and efficacy of once-daily application of CLS001 topical gel compared to vehicle gel in subjects with severe papulopustular rosacea.

NCT ID: NCT02576847 Completed - Rosacea Clinical Trials

Study to Evaluate the Long-term Safety of a Once-Daily Omiganan Topical Gel

Start date: October 2015
Phase: Phase 3
Study type: Interventional

This study evaluates the long-term safety of once-daily application of Omiganan topical gel in subjects with severe papulopustular rosacea.

NCT ID: NCT02576717 Completed - Multiple Sclerosis Clinical Trials

A Multi-Site, Open-Label Extension Trial of Oral RPC1063 in Relapsing Multiple Sclerosis

Start date: October 16, 2015
Phase: Phase 3
Study type: Interventional

The purpose of the trial is to determine the safety and efficacy of RPC1063 in patients with relapsing multiple sclerosis.