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NCT ID: NCT00255541 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 4 Tesaglitazar vs. Glibenclamide

Start date: September 2004
Phase: Phase 3
Study type: Interventional

This is a 52-week randomized, double-blind, parallel-group, multi-center, active-controlled (glibenclamide) study of tesaglitazar in patients with type 2 diabetes, not adequately controlled on diet and lifestyle advice alone during the run-in period. The study comprises a 6 week placebo single blind run in period followed by a 52-week double blind treatment period and a 3-week follow-up period. Tesaglitazar and glibenclamide will be titrated to optimal effect or highest tolerable dose during the first 12 weeks.

NCT ID: NCT00252876 Terminated - Type 2 Diabetes Clinical Trials

GALLEX 1 - Long Term Extension Study in Patients With Type 2 Diabetes

Start date: March 2005
Phase: Phase 3
Study type: Interventional

This is a 107-week open-label, multi-center long-term extension study from GALLANT studies 2/22, 5, 7, 8 and 14 to monitor the safety and tolerability of oral tesaglitazar 1 mg in patients with type 2 diabetes during up to 104 weeks of treatment. The total duration, including treatment and follow-up, is 107 weeks.

NCT ID: NCT00252837 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 22 Tesaglitazar vs. Placebo

Start date: April 2005
Phase: Phase 3
Study type: Interventional

This is a 24-week randomized, double-blind, parallel-group, multi-center, placebo-controlled study of tesaglitazar (0.5 and 1 mg) in patients with type 2 diabetes, not adequately controlled on diet and lifestyle advice alone during the run-in period. The study comprises a 6-week single-blind placebo run-in period, followed by 24-week treatment period and a 3-week follow-up period. The study design of GALLANT 2 is identical to GALLANT 22; the blinded study data from GALLANT 2 will be transferred to the GALLANT 22 database and will be analyzed together with the data from GALLANT 22 clinical study.

NCT ID: NCT00251953 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 8 Tesaglitazar Add-on to Metformin

Start date: July 2004
Phase: Phase 3
Study type: Interventional

This is a 24-week randomized double-blind, parallel-group, multi-center, placebo-controlled study of tesaglitazar (0.5 mg and 1 mg) given as add-on therapy to metformin in patients with type 2 diabetes, not adequately controlled on optimized metformin treatment and on diet/lifestyle advice during the titration and run-in period. The study comprises a 2-week enrollment period, 6 week placebo metformin titration period, 2-week single-blind run-in period, followed by a 24-week double blind treatment period and a 3-week follow-up period

NCT ID: NCT00251940 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 7 Tesaglitazar Add-on to Sulphonylurea

Start date: July 2004
Phase: Phase 3
Study type: Interventional

This is a 24-week randomized double-blind, parallel-group, multi-center, placebo-controlled study of tesaglitazar (0.5 mg and 1 mg) given as add-on therapy to sulphonylurea in patients with type 2 diabetes, not adequately controlled on optimized sulphonylurea treatment and on diet/lifestyle advice during the titration and run-in period. The study comprises a 2-week enrollment period, 6 week placebo metformin titration period, 2-week single-blind run-in period, followed by a 24-week double blind treatment period and a 3-week follow-up period

NCT ID: NCT00089804 Terminated - Lupus Nephritis Clinical Trials

Study of LJP 394 in Lupus Patients With History of Renal Disease

ASPEN
Start date: October 2004
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to determine whether abetimus sodium is more effective than placebo in delaying time to renal flare in SLE patients with a history of renal disease.