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NCT ID: NCT01421147 Completed - Clinical trials for Diabetes Mellitus, Type 1

A Study in Adults With Type 1 Diabetes

ELEMENT 1
Start date: August 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effectiveness and safety of LY2963016 versus Lantus when taken once daily in combination with insulin lispro before meals three times a day.

NCT ID: NCT01420601 Completed - Clinical trials for Renal Cell Carcinoma

Temsirolimus (Torisel) Special Investigation (Regulatory Post Marketing Commitment Plan)

Start date: September 2011
Phase:
Study type: Observational

To confirm the safety of the long-term use of TORISEL 25 mg for Intravenous Drip Infusion particularly for the onset of interstitial lung disease from Weeks 25 to 96 after the start of administration.

NCT ID: NCT01420081 Terminated - Clinical trials for Endometrial Neoplasms

A Study Of Two Dual PI3K/mTOR Inhibitors, PF-04691502 And PF-05212384 In Patients With Recurrent Endometrial Cancer

Start date: January 19, 2012
Phase: Phase 2
Study type: Interventional

This study will investigate the individual safety and efficacy of two dual PI3K/mTOR inhibitors in patients with recurrent endometrial cancer.

NCT ID: NCT01419717 Completed - Clinical trials for Bone Metastases in Subjects With Advanced Breast Cancer

Open-Label Access Protocol of Denosumab for Subjects With Advanced Cancer

Start date: November 22, 2011
Phase: Phase 3
Study type: Interventional

This trial will facilitate access to denosumab for adults with advanced cancer who have participated in a denosumab phase 3 study until denosumab is approved and available for sale.

NCT ID: NCT01419665 Completed - Follicular Lymphoma Clinical Trials

GP2013 in the Treatment of Patients With Previously Untreated, Advanced Stage Follicular Lymphoma (ASSIST_FL)

ASSIST_FL
Start date: December 1, 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate comparability of the ORR in patients with previously untreated, advanced stage FL who receive GP2013-treatment to patients who receive MabThera-treatment.

NCT ID: NCT01419327 Completed - Hyperphosphatemia Clinical Trials

Fosrenol Post-marketing Surveillance for Hemodialysis in Japan

FOSRENOL-HD
Start date: March 23, 2009
Phase:
Study type: Observational

This study is a regulatory post marketing surveillance in Japan, and it is a local prospective and observational study of patients in hemodialysis who received Fosrenol for hyperphosphatemia. The objective of this study is to assess safety and efficacy of using Fosrenol in clinical practice. A total 3,000 patients will be recruited and followed 5 years.

NCT ID: NCT01419015 Completed - Clinical trials for Aortic Valve Stenosis

PREVAIL-20J - Transfemoral Placement of 20mm Aortic Balloon Expandable Transcatheter Valve Trial

PREVAIL-20J
Start date: June 2011
Phase: N/A
Study type: Interventional

A single arm, prospective multicenter non-randomized pivotal clinical trial evaluating the 20mm Edwards SAPIEN XT™ transcatheter heart valve (model 9300TFX), NovaFlex™ transfemoral delivery system, and crimper accessories. The trial includes a premarket pivotal cohort to evaluate the system performance as well as a post market clinical follow-up phase involving long term follow-up of all patients to evaluate the safety of investigational devices up to 5 years.

NCT ID: NCT01417156 Completed - Pulmonary Fibrosis Clinical Trials

Safety and PK Study of BIBF 1120 in Japanese Patients With IPF: Follow up Study From 1199.31(NCT01136174)

Start date: September 2011
Phase: Phase 2
Study type: Interventional

Primary objective of this study is to investigate the long-term tolerability and safety profile of BIBF 1120 on top of pirfenidone treatment in patients with Idiopathic Pulmonary Fibrosis who have completed a prior clinical trial of BIBF 1120 (1199.31). Secondary objectives are to assess effects on some efficacy criteria during long term treatment with BIBF 1120 on top of pirfenidone.

NCT ID: NCT01416155 Completed - Multiple Sclerosis Clinical Trials

Extension Study to Evaluate Safety and Efficacy of Natalizumab in Japanese Participants With Relapsing-Remitting Multiple Sclerosis

Start date: October 2010
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to further evaluate the long-term safety and tolerability profiles of BG00002 (natalizumab) in Japanese participants with relapsing-remitting multiple sclerosis (RRMS). The secondary objective of this study is to further evaluate the long-term efficacy profile of BG00002 in Japanese participants with RRMS.

NCT ID: NCT01415427 Completed - MPS IVA Clinical Trials

Long-Term Efficacy and Safety Extension Study of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

Start date: July 2011
Phase: Phase 3
Study type: Interventional

This Phase 3 extension study will evaluate the long-term efficacy and safety of BMN 110 2.0 mg/kg/week and/or BMN 110 2.0 mg/kg/every other week in patients with mucopolysaccharidosis IVA (Morquio A Syndrome).