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NCT ID: NCT01605877 Completed - Cataracts Clinical Trials

AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan

Start date: May 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.

NCT ID: NCT01604343 Completed - Clinical trials for Arthritis, Rheumatoid

A Study of CNTO 136 (Sirukumab), Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Disease-Modifying Antirheumatic Drug (DMARD) Therapy (SIRROUND-D)

Start date: August 15, 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy of sirukumab as measured by the reduction of the signs and symptoms of rheumatoid arthritis (RA) and inhibition of radiographic progression in patients with active RA who are unresponsive to treatment with disease-modifying antirheumatic drugs (DMARD).

NCT ID: NCT01604161 Completed - Turner Syndrome Clinical Trials

Non-interventional Study of Patients Using Norditropin® for Growth Hormone Deficiency or Turner Syndrome

NordiPAD
Start date: May 2005
Phase: N/A
Study type: Observational

This study is conducted in Japan. The aim of this study is to collect information about the efficacy and safety of Norditropin® (somatropin) in the long-term treatment of short stature with GHD (Growth Hormone Deficiency) where epiphysial discs are not closed and short stature with Turner Syndrome where epiphysial discs are not closed.

NCT ID: NCT01603095 Completed - Achondroplasia Clinical Trials

A Multicenter, Multinational Clinical Assessment Study for Pediatric Patients With Achondroplasia

Start date: April 2012
Phase:
Study type: Observational

Multicenter, multinational study to collect consistent baseline growth measurements on pediatric patients with Achondroplasia being considered for subsequent enrollment in future studies sponsored by BioMarin. No study drug is administered.

NCT ID: NCT01602601 Completed - Clinical trials for Mucopolysaccharidosis II

A Study to Test the Possibility of Cross Reaction Induced by the Idursulfase Drug to GSK2788723

Start date: April 9, 2012
Phase: N/A
Study type: Observational

Study IDS116406 will be a non-interventional, phlebotomy study in Hunter Syndrome patients who are currently being treated with idursulfase, an enzyme replacement therapy, and in at least a single patient who is naïve to treatment, if possible to recruit. All patients enrolled into the study will have a single blood draw for the analysis of antibodies induced by this enzyme replacement therapy (idursulfase). Patient samples with positive responses to antibodies induced by idursulfase will be used to further evaluate whether the antibodies induced by idursulfase bind to GSK2788723 molecules in vitro and if these antibodies neutralize the bioactivity of GSK2788723 in vitro. Each subject will have a screening visit, which may occur at their regularly scheduled out-patient visit. If the patient consents to participate in the study, a blood sample (total volume of approximately 3mL) for immunogenicity analysis will be drawn before their current treatment infusion

NCT ID: NCT01602562 Completed - Herpes Simplex Clinical Trials

Valaciclovir Hydrochloride Phase III for Hematopoietic Stem Cell Transplantation Patients

Start date: May 7, 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the preventive efficacy for HSV infection and safety of valaciclovir (VACV) in the adult and pediatric HSCT patients.

NCT ID: NCT01602289 Completed - Lymphoma Clinical Trials

A Study of LY2875358 in Japanese Participants With Advanced Cancer

Start date: June 2012
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and tolerability of LY2875358 in Japanese participants with cancer that is advanced and/or may have spread to another part of the body.

NCT ID: NCT01600729 Completed - Facial Rhytides Clinical Trials

Reliability of the Facial Wrinkle Scale in Japanese Subjects

Start date: June 2012
Phase: N/A
Study type: Observational

This study will evaluate the inter-rater and intra-rater reliability of the Facial Wrinkle Scale with Asian Photonumeric Guide (FWS-A) in Japanese subjects.

NCT ID: NCT01600001 Completed - Clinical trials for Chronic Idiopathic Constipation

A Exploratory Study of KWA-0711 in Patients With Chronic Idiopathic Constipation (CIC)

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of KWA-0711 in Chronic Idiopathic Constipation (CIC) patients.

NCT ID: NCT01599819 Completed - Hemophilia A Clinical Trials

BAX 855 Dose-Escalation Safety Study

Start date: September 30, 2011
Phase: Phase 1
Study type: Interventional

The objectives of this study are to assess the tolerability and safety after single dose treatments of BAX 855 in previously treated patients (PTPs) with severe hemophilia A, to determine the pharmacokinetic (PK) parameters of BAX 855 compared in crossover with ADVATE, and to evaluate the impact of anti-polyethylene glycol (PEG) antibodies on PK parameters.